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Molecular Interactions in Bioseparations
Rapid advances in molecular biology have accelerated the production of a great number of protein-based therapeutic agents. The major cost in producing these proteins appears to be associated with their purification from the complex mixture of the crude extract. A major challenge to the protein biochemist and the biochemical engineer is the development of rapid, efficient, and cost-effective purification systems. This volume presents state-of-the-art reviews of current methods used in the purifica tion of biological macromolecules that are based on molecular interactions. Thus, the major emphasis is placed on affinity-related techniques. Part I provides a general introduction to affinity chro...
Japan's Favorite Mon-star
Bigger, badder, and more durable than Hollywood's greatest action heroes, Godzilla emerged from the mushroom cloud of an H-bomb test in 1954 to trample Tokyo. More than 40 years later, he reigns as the undisputed monarch of movie monsters, with legions of fans spanning several generations and countless international boundaries.
Polymeric Separation Media
This volume is a eoLleetion of manuseripts based on presenta tions at a symposium "Polymerie Separation Media" organized for the Seeond Chemieal Congress of the North Ameriean Continent held in Las Vegas, August 24-29, 1980. The symposium was organized to bring together researehers in the expanding field of separations based on polymerie media. A diverse eross-seetion of re.seareh areas were presented, whieh were linked by the aetive separation agent being a polymerie material. I would like to thank the authors for their endeavours and the audienee for their partieipation, espeeially in light of the late change of venue for this meeting. Finally I am indebted to the Division of Polymer Chemi...
The Expanding World of Chemical Engineering
This new edition of The Expanding World of Chemical Engineering provides an overview of recent and future developments in chemical engineering and future aspects in chemical engineering. The book is written by leading researchers in various fields of expertise and covers most important topics in chemical engineering. The topics covered include; computer application, material design, supercritical fluid technology, colloid and powder technology, new equipment, bio and medical technology and environmental preservation and remediation. This is a valuable book for students at all levels as well as for practitioners in chemical engineering and industry.
Handbook of Nonmedical Applications of Liposomes, Vol IV From Gene Delivery and Diagnosis to Ecology
Liposomes have become an important model in fundamental biomembrane research, including biophysical, biochemical, and cell biological studies of membranes and cell function. They are thoroughly studied in applications, such as drug delivery systems in medical applications and as controlled release systems, microencapsulating media, signal carriers, support matrices, and solubilizers in other applications. While medical applications have been extensively reviewed in recent literature, there is a need for easily accessible information on applications for liposomes beyond pharmacology and medicine.
Biochemical Engineering
Completely revised, updated, and enlarged, this second edition now contains a subchapter on biorecognition assays, plus a chapter on bioprocess control added by the new co-author Jun-ichi Horiuchi, who is one of the leading experts in the field. The central theme of the textbook remains the application of chemical engineering principles to biological processes in general, demonstrating how a chemical engineer would address and solve problems. To create a logical and clear structure, the book is divided into three parts. The first deals with the basic concepts and principles of chemical engineering and can be read by those students with no prior knowledge of chemical engineering. The second p...
Methods for Affinity-Based Separations of Enzymes and Proteins
One major concern of biotechnology is either using enzymes or producing them. Enzyme/protein production is therefore an important starting point for biotechnology. Bioseparation or Downstream Processing constitutes about 40-90% of the total production cost. Driven by economics, highly selective technologies applicable to large-scale processing have emerged during the last decade. These technologies are slowly diffusing to enzymologists who are working on a smaller scale, looking for fast and efficient purification protocols. The affinity-based techniques (including precipitation, two-phase extractions, expanded bed chromatography, perfusion chromatography and monoliths) described in this volume provide current and new cutting-edge methods. Consequently, the book is of main interest to researchers in biochemistry, biochemical engineering and biotechnology, working either in academic or industrial sectors.
