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A wide range of microbiologists, molecular biologists, and molecular evolutionary biologists will find this new volume of singular interest. It summarizes the present knowledge about the structure and stability of microbial genomes, and reviews the techniques used to analyze and fingerprint them. Maps of approximately thirty important microbes, along with articles on the construction and relevant features of the maps are included. The volume is not intended as a complete compendium of all information on microbial genomes, but rather focuses on approaches, methods and good examples of the analysis of small genomes.
In Detecting Chinese Modernities: Rupture and Continuity in Modern Chinese Detective Fiction (1896–1949), Yan Wei historicizes the two stages in the development of Chinese detective fiction and discusses the rupture and continuity in the cultural transactions, mediation, and appropriation that occurred when the genre of detective fiction traveled to China during the first half of the twentieth century. Wei identifies two divergent, or even opposite strategies for appropriating Western detective fiction during the late Qing and the Republican periods. She further argues that these two periods in the domestication of detective fiction were also connected by shared emotions. Both periods expressed ambivalent and sometimes contradictory views regarding Chinese tradition and Western modernity.
First multi-year cumulation covers six years: 1965-70.
This book presents detailed methods on a variety of aspects of Salmonella research, focusing on those which provide landmarks for future discovery. It is the first comprehensive volume of methods and protocols for studying Salmonella and will be indispensable to researchers engaged in the study of Salmonella, and enterobacteria in general. Each chapter provides a short overview of the topic, followed by detailed explanations of techniques.
Burkholderia pseudomallei and B. mallei, causes melioidosis and glanders, respectively, which are two endemic infectious diseases in many parts of the world. The recent reports of glanders outbreaks in horses in Pakistan and Bahrain and the increasing incidence of human melioidosis in Thailand and other tropical regions have resulted in increased research efforts to prevent these diseases. Moreover, both B. mallei and B. pseudomallei exhibit an intriguing intracellular life cycle including the induction of actin tail formation and cell fusion and thereby have developed as model organisms in infection biology. This Research Topic summarizes recent progress to understand these pathogens at the molecular level, with emphasis in their virulence traits, host pathogen interactions, population structure and potential targets for therapeutic intervention and vaccine development.
The oral cavity harbors an immense diversity of microorganisms, including bacteria, fungi, archaea, protozoa and viruses. At health, oral microbial community is thought to be in a state of homeostasis, even after numerous perturbations (e.g., toothbrushing, food intake) a day. The breach in this homeostasis can occur for instance if the perturbations become too excessive (e.g., frequent carbohydrate intake leading to acidification of the community) or the host is compromised (e.g., inadequate immune response resulting in persistent inflammation of periodontal tissue). Aggressive antimicrobial therapy (e.g., antibiotics in case of periodontal disease or preventive antibiotic therapy before an...