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Statistical analysis of multi-cell recordings: linking population coding models to experimental data
Modern recording techniques such as multi-electrode arrays and 2-photon imaging are capable of simultaneously monitoring the activity of large neuronal ensembles at single cell resolution. This makes it possible to study the dynamics of neural populations of considerable size, and to gain insights into their computations and functional organization. The key challenge with multi-electrode recordings is their high-dimensional nature. Understanding this kind of data requires powerful statistical techniques for capturing the structure of the neural population responses and their relation with external stimuli or behavioral observations. Contributions to this Research Topic should advance statist...
Neuroprosthetics
A study of neuroprosthetics. It is broadly divided into three sections which address: neuroanatomy and neurophysiology, biomaterials and biocompatibility, stimulation and recording techniques; clinical applications of neuroprosthetics; and future developments.
Optogenetics
This book provides applications for the revolutionary technique of optogenetics, which combines genetic and optical methods to observe the function of neurons.
A Most Interesting Problem
Leading scholars take stock of Darwin's ideas about human evolution in the light of modern science In 1871, Charles Darwin published The Descent of Man, a companion to Origin of Species in which he attempted to explain human evolution, a topic he called "the highest and most interesting problem for the naturalist." A Most Interesting Problem brings together twelve world-class scholars and science communicators to investigate what Darwin got right—and what he got wrong—about the origin, history, and biological variation of humans. Edited by Jeremy DeSilva and with an introduction by acclaimed Darwin biographer Janet Browne, A Most Interesting Problem draws on the latest discoveries in fie...
Demystifying the Brain
This book presents an emerging new vision of the brain, which is essentially expressed in computational terms, for non-experts. As such, it presents the fundamental concepts of neuroscience in simple language, without overwhelming non-biologists with excessive biological jargon. In addition, the book presents a novel computational perspective on the brain for biologists, without resorting to complex mathematical equations. It addresses a comprehensive range of topics, starting with the history of neuroscience, the function of the individual neuron, the various kinds of neural network models that can explain diverse neural phenomena, sensory-motor function, language, emotions, and concluding with the latest theories on consciousness. The book offers readers a panoramic introduction to the “new brain” and a valuable resource for interdisciplinary researchers looking to gatecrash the world of neuroscience.
Methods for Imaging Cell Membranes
· Measuring membrane protein distributions using single-molecule localisation microscopy (SMLM) · Measuring membrane protein dynamics and diffusion using fluorescence correlation spectroscopy (FCS) · Mapping membrane lipid backing using environmentally sensitive fluorescence probes · Mapping membrane thickness and rigidity using atomic force microscopy · Mapping membrane proteins and the cytoskeleton using electron microscopy
The Woman Who Changed Her Brain
Barbara Arrowsmith-Young was born with severe learning disabilities that caused teachers to label her slow, stubborn—or worse. As a child, she read and wrote everything backward, struggled to process concepts in language, continually got lost, and was physically uncoordinated. She could make no sense of an analogue clock. But by relying on her formidable memory and iron will, she made her way to graduate school, where she chanced upon research that inspired her to invent cognitive exercises to “fix” her own brain. The Woman Who Changed Her Brain interweaves her personal tale with riveting case histories from her more than thirty years of working with both children and adults. Recent di...
Toward Brain-computer Interfacing
This volume presents a timely overview of the latest BCI research, with contributions from many of the important research groups in the field.
Toward Human-Level Artificial Intelligence
Is a computer simulation of a brain sufficient to make it intelligent? Do you need consciousness to have intelligence? Do you need to be alive to have consciousness? This book has a dual purpose. First, it provides a multi-disciplinary research survey across all branches of neuroscience and AI research that relate to this book’s mission of bringing AI research closer to building a human-level AI (HLAI) system. It provides an encapsulation of key ideas and concepts, and provides all the references for the reader to delve deeper; much of the survey coverage is of recent pioneering research. Second, the final part of this book brings together key concepts from the survey and makes suggestions...
