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Guanidines
In 1978, we had the first research meeting of guanidine compound analysis in Okayama, Japan. The purpose of the meeting was to standardize the methods of analyzing guanidino compounds, because the analytic methods, even, for example, that of normal plasma, were quite different from laboratory to laboratory at that time. More than ten laboratories joined in this research project. Thereafter, the purpose of the annual meetings was extended to cover general biochemistry of guanidino compounds, and every meeting has served to promote our mutual growth and progress. The last meeting of the Japan Guanidino Compounds Research Association in 1982 brought together more than 80 members, and about 30 p...
Cyanide
This collection of papers from the 2001 TMS Annual Meeting held in New Orleans focuses on five issues concerning cianide: production and uses, processing practices and innovations, recovery and destruction, fundamentals and alternatives. There is also a section about the environmental movement.
Toxicology of Cyanides and Cyanogens
The basic and applied toxicology of cyanides and cyanogens has widespread commercial, occupational, environmental, clinical, forensic, military, and public health implications. This book provides a detailed and updated reference describing the properties, uses, general and human toxicology, clinical recognition, diagnosis and medical management, and countermeasures is therefore required in academic, medical, occupational, environmental, medico-legal, regulatory, emergency response, and military arenas. Edited by a world-renowned team of experts from academia, defense and industry, this book will be an invaluable reference for professionals, researchers and students in cyanide and cyanogens.
Handbook of Toxicology of Chemical Warfare Agents
This groundbreaking book covers every aspect of deadly toxic chemicals used as weapons of mass destruction and employed in conflicts, warfare and terrorism. Including findings from experimental as well as clinical studies, this one-of-a-kind handbook is prepared in a very user- friendly format that can easily be followed by students, teachers and researchers, as well as lay people. Stand-alone chapters on individual chemicals and major topics allow the reader to easily access required information without searching through the entire book.This is the first book that offers in-depth coverage of individual toxicants, target organ toxicity, major incidents, toxic effects in humans, animals and w...
Toxicology
Toxicology is a comprehensive text for researchers and graduate students in toxicology and public health. It addresses every aspect of the field, starting with the fundamentals and incorporating such areas as organ toxicology, applications, and environmental toxicology. In addition to covering the traditional subject matter of toxicology, special emphasis has been placed on recent areas of interest, such as risk assessment, apoptosis, and methodical developments.Key Features* Comprehensive text, covering all aspects of the field of toxicology* Analyzes the importance of toxicokinetics and metabolism as well as cellular targets for the mechanisms of toxic effects* Identifies the various classes of chemical compounds responsible for the toxic effects* Describes the approaches and methods used by various disciplines which investigate toxic effects and their prevention* Adapted from a very successful German text, this edition is completely revised and expanded * The text is well illustrated with diagrams, charts, and tables
Taurine
The underlying philosophy of these two symposia on taurine remains the same as all those that have been held previously: the best way to remain current in the subject matter is to talk directly with the investigators at the forefront of the field. Thus, we brought together some 50 individuals from 11 different countries who have keen interests and active research programs in the many-faceted areas of taurine research. The meetings were held on October 8-10, 1991, in an elegant setting in a resort area at Orange Beach, Alabama, approximately 50 miles outside of Mobile on the Gulf Coast. The meetings were programmed as two separate Symposia held sequentially. The first symposia on October 8 wa...
Taurine 4
Mitochondria from mammalian tissues possess an elaborate system for 2+ 2+ transporting Ca across their inner membrane which consists of Ca import, 2+ via the Ca uniporter, in response to the mitochondrial membrane 2+ + potential ?? and of Ca release by an antiport system in exchange for H + 9,23 or Na (see Fig. l) . Because the uniporter is dependent upon the external 2+ 2+ 2+ 2+ Ca concentration ([Ca ]), mitochondria accumulate Ca until the [Ca ] o o 2+ decreases to the level at which the uniporter activity balances the Ca efflux. 2+ The [Ca ] at which the uniporter and efflux activities are equal is defined o the “setpoint” andcorresponds to values between 0.3-3μM. 2+ Figure 1. The Ca transport system of the inner membrane of mammalian mitochondria. U, + 2+ + + uniporter. I, Na -independent efflux mechanism or Ca /2H exchanger. D, Na -dependent 2+ + efflux mechanism or Ca /2Na exchanger. PTP, permeability transition pore. FP, 11 flavoprotein. ?? membrane potential. ? pH gradient. Adapted from .
