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Nutrition Support for Infants and Children at Risk
Adequate nutrition is especially important during infancy and childhood, where even short periods of malnutrition have long-lasting effects on growth, development and health in adult life. There are several high-risk scenarios for the development of malnutrition, which are the focus of the current publication: Atopic diseases, gastrointestinal disorders, and preterm delivery. For the pediatric allergist it is important to understand the mechanisms regulating IgE responses to food proteins since they may also be the earliest markers for the atopic march. As breastfeeding seems to have only limited effects regarding the atopic march, other measures to modulate infantile immune responses have t...
Drivers of Innovation in Pediatric Nutrition
When developing a new product, many obstacles have to be overcome from the idea to the shelf: know-how from different subject areas is called for to create a product that is not only technically feasible, but also complies with regulations and meets consumer needs and preferences. This book addresses and tries to identify forces that potentially drive innovation in pediatric nutrition, an endeavor which surpasses research, clinical and academic thinking. The likelihood of translating innovative research concepts into practical applications depends on a large number of factors; Clinical studies, adherence to regulatory standards and environments of various countries, policy and politics on child health and nutrition, marketing issues, economic considerations as well as the state of food technology all determine whether and how a product can be brought to the market. Expectations and response of both consumers and health care professionals are likewise of very high importance. Due to its broad scope, this publication is of interest to everyone involved in one way or another in the development and launch of new products for pediatric nutrition.
Pediatric Nutrition in Practice
There is no other time in life when the provision of appropriate nutrition is of greater importance than during infancy and childhood. During this phase of life, characterized by rapid growth and development, an adequate amount and composition of nutrients both in health and disease are of key importance for growth, functional outcomes such as cognition and immune response, and long-term well-being. To provide concise information to readers who seek quick guidance on practical relevant issues in the nutrition of infants, children and adolescents, the editors have developed this compact reference book as busy physicians and other healthcare professionals often find it difficult to devote sufficient time to study elaborate and extensive books on just one aspect of their practice. Moreover, due to the insightful input of a global editorial board, challenges both in affluent and poorer populations are addressed, thus providing a truly international perspective which further contributes to the unique worth of this book.
Pediatric Nutrition in Practice
There is no other time in life when the provision of adequate and balanced nutrition is of greater importance than during infancy and childhood. During this dynamic phase characterized by rapid growth, development and developmental plasticity, a sufficient amount and appropriate composition of nutrients both in health and disease are of key importance for growth, functional outcomes such as cognition and immune response, and the metabolic programming of long-term health and well-being. This compact reference text provides concise information to readers who seek quick guidance on practical issues in the nutrition of infants, children and adolescents. After the success of the first edition, which sold more than 50'000 copies in several languages, the editors prepared this thoroughly revised and updated second edition which focuses again on nutritional challenges in both affluent and poor populations around the world. Serving as a practical reference guide, this book will contribute to further improving the quality of feeding of healthy infants and children, as well as enhancing the standards of nutritional care in sick children.
Pediatric and Inflammatory Bowel Disease
Chronic inflammatory bowel disease (IBD) encompasses Crohn's disease, ulcerative colitis and indeterminate colitis. The distinct phenotype in pediatric and adolescent patients and the difference from adult IBD make early-onset IBD a unique subgroup requiring specific therapeutic considerations. In this book, leading experts from the USA, Europe and Israel present new data on the genetics, epidemiology, pathology and pathogenesis of pediatric IBD. Imaging and endoscopy in the diagnosis of IBD are also discussed. Extensive coverage is given to disease management, i.e. pharmacological, nutritional and surgical approaches, with special emphasis on growth failure and delayed puberty. The important topic of transition from pediatric to adult medical care is highlighted and a clinical and developmental timeline is proposed.Offering practical information on IBD in infants, toddlers, children, adolescents and young adults, this book is essential reading for gastroenterologists, in particular pediatric gastroenterologists and trainees, as well as general pediatricians and nutritionists.
Nutrition, Gut Microbiota and Immunity: Therapeutic Targets for IBD
Inflammatory Bowel Disease (IBD) is a chronic debilitating disorder that occurs at any age and in populations around the world. Its pathogenesis is believed to involve a combination of genetic susceptibility, immune and external environmental factors, including the gut microbiota. Changing factors such as diet and the human gut microbiota may thus be a viable alternative to suppressing the innate and adaptive immune responses. The book at hand starts with a summary of the current understanding of the epidemiology and biologic underpinnings that manifest as IBD. Next, the gut microbiota, its function, and how it may interact with nutritional status in perpetuating IBD are looked at, followed by discussions on the potential for manipulation of the gut microbiota through the use of prebiotics, probiotics, antibiotics, and fecal transplantation. Chapters on the current role of and future prospects for nutritional interventions in the management of IBD complete the topics presented.
Helicobacter pylori Research
This book provides the current updated knowledge on all essential aspects in the rapidly evolving area of Helicobacter pylori research. H. pylori is a class I carcinogen and one of the most common infections in the world. While most people colonized by H. pylori will remain asymptomatic, up to 20 % of them may develop serious gastroduodenal disease such as peptic ulcers or gastric cancer. H. pylori is the only known bacterium linked to the development of cancer and consequently is an important focus of research. Outstanding international experts from diverse scientific disciplines contribute here to give detailed insights into the current understanding concerning the physiology and role of t...
Microbial Host-interaction
Most indigenous microbes occur in the intestinal tract, and their interactions with the host are largely unknown. Current understanding of host-microbe interactions links early microbial contact to the origin of disease, a theory that has its roots in the hygiene hypothesis. Modern life style appears to deprive the infant of conditions that provide adequate anti-inflammatory or tolerogenic stimuli upon antigen encounter. Thus, maturational signals from the environment and the diet are insufficient to adequately shape the immune system. This publication deals with the relationship between the gut microbiota as well as altered pattern of early microbial contact and the origin of human disease. New aspects of the original hygiene hypothesis are discussed in relation to disorders spanning from allergy and autoimmunity to obesity.The results presented suggest that all these disorders may be linked to aberrant antigen absorption and immune responses associated with dysfunction of mucosal defense. Researchers, clinicians and students interested in the interaction of the host with indigenous gut bacteria and the consequences for human health will find this publication of utmost interest.
Paediatric Parenteral Nutrition
Parenteral nutrition in general is required if nutritional needs cannot be met by oral or enteral feeding. In the paediatric patient, its initiation depends both on individual circumstances and the age and size of the infant or child. This compact reference work on parenteral nutrition in children is based on the 'Guidelines for Paediatric Parenteral Nutrition' that have been developed jointly by the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) and the European Society for Clinical Nutrition and Metabolism (ESPEN), in collaboration with the European Society for Paediatric Research (ESPR).These guidelines were based on systematic literature reviews as w...
