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This detailed volume presents a variety of mouse models for cancer studies, from leukemia and lymphoma models to different types of subcutaneous and orthotopic models. Models for the healing process and the assessment of the immune response after local ablative therapies are also included, as well as imaging techniques that allow for the visualization of cancer at the cellular and tissue level. The book closes with a detailed description of necropsy, which is essential for obtaining good biomaterial for translational research. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Mouse Models of Cancer: Methods and Protocols serves as an ideal guide to these controlled and reproducible model experimental systems to study different aspects of cancer biology, including prevention, development, progression, and treatment.
A reflection of the intense study of the effects of electromagnetic fields on living tissues that has taken place during the last decades, Advanced Electroporation Techniques in Biology and Medicine summarizes most recent experimental findings and theories related to permeabilization of biomembranes by pulsed electric fields. Edited by experts and
This volume is a comprehensive, state-of-the-science treatment of the acquisition of different Indo- and Non-Indo-European languages in different contexts (i.e., L1, L2, L3/Ln, bi/multilingual language, heritage languages, pathology and language impairment and sign language acquisition) conducted within the generative framework. It also encompasses the diversity of methodologies and issues that can be found with contemporary research in the field. The different chapters contain original research from several different angles and provide a basis for dialogue between researchers working on diverse projects with the aim to further our understanding of how languages are acquired and, at the same time, refine and propose new theoretical constructs, such as complexity of linguistic features as a relevant factor forming children’s, adult’s and bilingual’s acquisition of syntactic, morphological, lexical and phonological structures.
Publikacija je zbornik povzetkov prispevkov 12. letnega srečanja Združenja za slovansko jezikoslovje (Slavic Linguistics Society) (Ljubljana, 21.–24. september 2017, v organizaciji Inštituta za slovenski jezik Frana Ramovša Znanstvenoraziskovalnega centra Slovenske akademije znanosti in umetnosti ter Oddelka za slavistiko, Oddelka za slovenistiko in Oddelka za primerjalno in splošno jezikoslovje Filozofske fakultete Univerze v Ljubljani). Zbornik vsebuje okrog 100 prispevkov, katerih avtorji so jezikoslovci iz Severne Amerike, Evrope, Rusije, Južne Koreje in Japonske, ki se ukvarjajo z znanstvenim preučevanjem slovanskih jezikov. V prispevkih so v duhu omogočanja enakih možnosti vsem in ohranjanja metodološkega pluralizma v znanosti zastopane različne jezikoslovne poddiscipline, teoretični modeli in metodološki pristopi, saj je glavni namen delovanja združevanja prav vzpostavljanje tvornega dialoga med njimi.
At present, less than 30% of researchers worldwide are women. Long-standing biases and gender stereotypes are discouraging girls and women away from science-related fields, and STEM research in particular. Science and gender equality are, however, essential to ensure sustainable development as highlighted by UNESCO. In order to change traditional mindsets, gender equality must be promoted, stereotypes defeated, and girls and women should be encouraged to pursue STEM careers. Therefore, Frontiers in Immunology is proud to offer this platform to promote the work of women scientists, across all fields of Cancer Immunity and Immunotherapy.
Electroporation is the forefront in tumor ablation. This book presents the basic principles and clinical applications of electroporation, including the latest research results and patient data. A comprehensive approach to the basic science behind the development of this ground-breaking technique and its introduction into clinical practice, the book discusses the entire spectrum of currently available reversible treatments, the emerging irreversible applications, and their impact on patient care. Clinical Aspects of Electroporation is the first book intended for clinicians on this extremely important and rapidly developing field.
Present Your Research to the World! The World Congress 2009 on Medical Physics and Biomedical Engineering – the triennial scientific meeting of the IUPESM - is the world’s leading forum for presenting the results of current scientific work in health-related physics and technologies to an international audience. With more than 2,800 presentations it will be the biggest conference in the fields of Medical Physics and Biomedical Engineering in 2009! Medical physics, biomedical engineering and bioengineering have been driving forces of innovation and progress in medicine and healthcare over the past two decades. As new key technologies arise with significant potential to open new options in ...
Koncept novega razlagalnega slovarja slovenskega knjižnega jezika opredeljuje vsebino in zgradbo sodobnega enojezičnega informativno-normativnega slovarja, ki nastaja na Inštitutu za slovenski jezik Frana Ramovša ZRC SAZU. Koncept v prvem poglavju pojasni osnovne lastnosti slovarja, njegov obseg in namen, v drugem poglavju je podrobno razčlenjena sestava slovarskega sestavka, tretje poglavje pa oriše proces redaktorskega dela. Slovar bo vseboval približno 100.000 slovarskih sestavkov, v katerih bodo opisane slovnične, pomenske in druge lastnosti eno- in večbesednih leksikalnih enot sodobne knjižne slovenščine. Vsakoletni slovarski prirastek bo objavljen na portalu Fran: slovarji ...
Delo prinaša besediloslovno analizo govorjenega diskurza. V ospredju zanimanja so načini, po katerih se v spontani neformalni konverzaciji vzpostavlja besedilna koherenca, ter analizirane okoliščine, ki vplivajo na to, ali je konverzacija koherentna ali ne. Prikazana so tudi kohezivna sredstva in načini, kako se v konverzaciji vzpostavljajo kohezivne vezi ter gradi (ko)referenčna mreža. Uporabljeni so štirje sodobni pristopi k analizi diskurza: pragmatična perspektiva, konverzacijska analiza, besediloslovje in funkcijsko jezikoslovje.