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The DNA Damage Response: Implications on Cancer Formation and Treatment
The ?eld of cellular responses to DNA damage has attained widespread recognition and interest in recent years commensurate with its fundamental role in the ma- tenance of genomic stability. These responses, which are essential to preventing cellular death or malignant transformation, are organized into a sophisticated s- tem designated the “DNA damage response”. This system operates in all living organisms to maintain genomic stability in the face of constant attacks on the DNA from a variety of endogenous by-products of normal metabolism, as well as exogenous agents such as radiation and toxic chemicals in the environment. The response repairs DNA damage via an intricate cellular signal...
Architecture as Experience
Architecture as Experience investigates the perception and appropriation of places across intervals of time and culture. The particular concern of the volume is to bring together fresh empirical research and animate it through contact with theoretical sophistication, without overwhelming the material. The chapters establish the continuity of a particular physical object and show it in at least two alternative historical perspectives, in which recognisable features are shown in different lights. The results are often surprising, inverting the common idea of a historic place as having an enduring meaning. This book shows the insight that can be gained from learning about earlier constructions of meaning which have been derived from the same buildings that stand before us today.
Teaching Civic Engagement Globally
A thriving and peaceful democracy requires an informed and engaged citizenry, but such citizenship must be learned. Educators around the globe are facing challenges in teaching politics in an era in which populist values are on the rise, authoritarian governance is legitimized, and core democratic tenets are regularly undermined by leaders and citizens alike. To combat anti-democratic outcomes and citizens' apathy, Teaching Civic Engagement Globally provides a wide range of pedagogical tools to help the current generation learn to effectively navigate debates and lead changes in local, national, and global politics. Contributors discuss key theoretical discussions and challenges regarding global civic engagement education, highlight successful evidence-based pedagogical approaches, and review effective ways to reach across disciplines and the global education community. Most importantly, the book provides tangible steps to link democratic education research with action that reflects contemporary global circumstances.
Teaching Civic Engagement
Teaching Civic Engagement provides an exploration of key theoretical discussions, innovative ideas, and best practices in educating citizens in the 21st century. The book addresses theoretical debates over the place of civic engagement education in Political Science. It offers pedagogical examples in several sub-fields, including evidence of their effectiveness and models of appropriate assessment. Written by political scientists from a range of institutions and subfields, Teaching Civic Engagement makes the case that civic and political engagement should be a central part of our mission as a discipline.
Kierkegaard's International Reception
As Kierkegaard's reputation grew, he was co-opted by a number of different philosophical and religious movements in different contexts throughout the world. This volume features the three tomes that attempt to record the history of this reception according to national and linguistic categories.
Clouds in a Glass of Beer
Liberally sprinkled with humor, these lessons will fascinate beginning physics students and other readers with chapters titled "On a Clear Day You Can't See Forever" and "Physics on a Manure Heap."
Demodiversity
We are living in a time when social and political authoritarianism appear to be gaining ground around the world. This book presents the democratic practices, spaces and processes that engage directly with the theoretical assumptions advanced by the epistemologies of the South, summoning other contexts and empirical realities that attest to the possibility of a renewal and deepening of democracy beyond the liberal and representative canon, which is embedded within a world capitalist system. The chapters in this book put forward the ideas of demodiversity, of high-intensity democracy, of the articulation between representative democracy and participatory democracy as well as, in certain contex...
The EU Timescape
The manner in which time is institutionalized is critical to how a political system works. Terms, time budgets and time horizons of collective and individual political actors; rights over timing, sequencing and speed in decision-making; and the temporal properties of policy matter to the distribution of power; efficiency and effectiveness of policy-making; and democratic legitimacy. This book makes a case for the systematic study of political time in the European Union (EU) - both as an independent and a dependent variable - and highlights the analytical value-added of a time-centred analysis. The book discusses previous scholarship on the institutionalization of political time and its consequences along the dimensions of polity, politics and policy; reviews dominant perspectives on political time, which centre on power, system performance and legitimacy; and presents case studies that illustrate the importance of time in the governance of the EU. This book was original published as a special issue of Journal of European Public Policy.
