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The Cerebellum and Its Disorders
The first comprehensive text on the cerebellum and its disorders for many years.
Handbook of Ataxia Disorders
This timely reference presents, for the first time, new findings in molecular genetics that are applicable to the epidemiology, pathogenesis, neuropathology, clinical features, and management of ataxia-bridging the gap between scientific and clinical practice. Organized by the distinctive ataxia disorders, their pathogenesis, and management-facilitating quick and efficient diagnoses! Providing complementary sections on the anatomy of the spinocerebellar system, its normal function, and a history of ataxia research and management, the Handbook of Ataxia Disorders clarifies the impact of identifying the molecular causes of ataxia offers in-depth analysis of dominant and recessive and nonheredi...
Genetics of Movement Disorders
Hereditary or genetic diseases featuring involuntary movements constitute a major aspect of the practice of neurology, functional neurosurgery, genetics, and many areas of basic and applied neuroscience research. Describing the current knowledge on these disorders, Genetics of Movement Disorders brings together information essential for clinicians, geneticists, and neuroscientists in one source. Utilizing a convenient and accessible format, the book is designed to allow easy identification of relevant information, with the overall organization of topics following established phenotypic classifications of movement disorders such as Parkinsonian syndromes, chorea, ataxia, and major categories ...
Handbook of Statistical Systems Biology
Systems Biology is now entering a mature phase in which the key issues are characterising uncertainty and stochastic effects in mathematical models of biological systems. The area is moving towards a full statistical analysis and probabilistic reasoning over the inferences that can be made from mathematical models. This handbook presents a comprehensive guide to the discipline for practitioners and educators, in providing a full and detailed treatment of these important and emerging subjects. Leading experts in systems biology and statistics have come together to provide insight in to the major ideas in the field, and in particular methods of specifying and fitting models, and estimating the...
Automation in Proteomics and Genomics
In the last decade DNA sequencing costs have decreased over a magnitude, largely because of increasing throughput by incremental advances in tools, technologies and process improvements. Further cost reductions in this and in related proteomics technologies are expected as a result of the development of new high-throughput techniques and the computational machinery needed to analyze data generated. Automation in Proteomics & Genomics: An Engineering Case-Based Approach describes the automation technology currently in the areas of analysis, design, and integration, as well as providing basic biology concepts behind proteomics and genomics. The book also discusses the current technological lim...
ECAI 2020
This book presents the proceedings of the 24th European Conference on Artificial Intelligence (ECAI 2020), held in Santiago de Compostela, Spain, from 29 August to 8 September 2020. The conference was postponed from June, and much of it conducted online due to the COVID-19 restrictions. The conference is one of the principal occasions for researchers and practitioners of AI to meet and discuss the latest trends and challenges in all fields of AI and to demonstrate innovative applications and uses of advanced AI technology. The book also includes the proceedings of the 10th Conference on Prestigious Applications of Artificial Intelligence (PAIS 2020) held at the same time. A record number of ...
The Theory and Practice of Experimental Philosophy
In recent years, developments in experimental philosophy have led many thinkers to reconsider their central assumptions and methods. It is not enough to speculate and introspect from the armchair—philosophers must subject their claims to scientific scrutiny, looking at evidence and in some cases conducting new empirical research. The Theory and Practice of Experimental Philosophy is an introduction and guide to the systematic collection and analysis of empirical data in academic philosophy. This book serves two purposes: first, it examines the theory behind “x-phi,” including its underlying motivations and the objections that have been leveled against it. Second, the book offers a practical guide for those interested in doing experimental philosophy, detailing how to design, implement, and analyze empirical studies. Thus, the book explains the reasoning behind x-phi and provides tools to help readers become experimental philosophers.
A Politics of Emancipation
Despite his influence in utopian studies and democratic theory, French philosopher Miguel Abensour (1939–2017) has yet to be fully discovered in the English-speaking world as only a fraction of his work has been translated. A Politics of Emancipation fills this void by translating a selection of his seminal essays into English for the first time. The Reader provides a systematic overview of Abensour's work and the two inseparable projects that govern his approach to political theory: on the one hand, a radical critique of all forms of domination and, on the other, a desire to conceptualize the political as the realm of freedom and emancipation. For Abensour, both projects are to be undertaken together in order to avoid the double trap of an evacuation of conflict from politics and the reduction of politics to a form of domination. In other words, a politics of emancipation requires a "ruthless" critique of domination coupled with an analysis of politics as the domain within which human beings experience freedom and equality.
Extraction et Gestion des Connaissances,
La sélection d'articles publiés dans le présent recueil constitue les actes des 21ème Journées Internationales Francophones "Extraction et Gestion des Connaissances" (EGC2021) qui se sont déroulées virtuellement du 25 au 29 janvier 2021. L'objectif de ces journées scientifiques est de rassembler dans un même lieu les chercheurs de disciplines connexe (Bases de Données, Statistiques, Apprentissage, Représentation des Connaissances, Gestion des Connaissances et Fouille de Données) et les ingénieurs qui mettent en oeuvre sur des données réelles des méthodes d'extraction et de gestion des connaissances. Cette conférence est un événement majeur fédérateur de la communauté fr...
Bayesian Networks in R
Bayesian Networks in R with Applications in Systems Biology is unique as it introduces the reader to the essential concepts in Bayesian network modeling and inference in conjunction with examples in the open-source statistical environment R. The level of sophistication is also gradually increased across the chapters with exercises and solutions for enhanced understanding for hands-on experimentation of the theory and concepts. The application focuses on systems biology with emphasis on modeling pathways and signaling mechanisms from high-throughput molecular data. Bayesian networks have proven to be especially useful abstractions in this regard. Their usefulness is especially exemplified by their ability to discover new associations in addition to validating known ones across the molecules of interest. It is also expected that the prevalence of publicly available high-throughput biological data sets may encourage the audience to explore investigating novel paradigms using the approaches presented in the book.
