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The Liver
In its Fifth Edition, this classic book retains its traditional strength of relating molecular physiology to understanding disease pathology and treatment as it explores the current state and future direction of hepatology. Painstakingly revised, this edition includes 60 new chapters. As in previous editions, a section called Horizons summarizes advances of extraordinary nature in areas expected to have a substantial impact on hepatology. The Fifth Edition’s Horizons section includes emerging topics such as tissue engineering of the liver, liver-directed gene therapy, decoding the liver cancer genome, and imaging cellular proteins and structure. To preserve essential background information which has not changed while making room for the panoply of major new contributions to understanding of liver disease, 14 chapters from the previous edition are freely available online at gastrohep.com. To view these chapters visit - http://www.gastrohep.com/theliver/
Cardiac Management in the Frail Elderly Patient and the Oldest Old
This book focuses specifically on the management of cardiovascular disease in elderly patients with particular frailties and in the “oldest old”. It is clearly explained how treatment in these patients differs from that in patients in their seventies who respond well to therapies and do not present frailties or organ failures. Although not young, the latter patients can be treated almost like any other patient, according to established guidelines. In contrast, the frail, compromised elderly and the oldest old require specific measures that target their needs, including with respect to underlying renal conditions. The book considers all those pathologies that have a high prevalence in the general population, explaining advanced treatment concepts and all aspects of assessment. Key clinical points are highlighted, and the text is supplemented with numerous informative figures and tables. The authors are respected experts, for the most part geriatric physicians, and the book is especially addressed to cardiologists, who may lack the described targeted information and treatment tools.
Mechanisms of Innate Neuroprotection
As clinical trials of pharmacological neuroprotective strategies in stroke have been disappointing, attention has turned to the brain's own endogenous strategies for neuroprotection. Two endogenous mechanisms have been recently characterized, ischemic preconditioning and ischemic postconditioning. In the present topic newly characterized mechanisms involved in preconditioning- and postconditioning- neuroprotection will be discussed. The understanding of the mechanisms involved in the neuroprotective pathways induced by preconditioning and postconditioning will be clinically relevant for identifying new druggable target for neurodegenerative disorder therapy. Furthermore, the importance of these neuroprotective strategies resides in that it might be easily translatable into clinical practice. Therefore, the data presented here will highlight the capacity of ischemic preconditioning and postconditioning to be of benefit to humans.
The Paulicians
Disavowing their traditional portrayal as the progenitors of medieval Christian dualism, this book recasts the Paulicians as broadly conventional Christians inspired by the apostle Paul. Using previously neglected Paulician testimony and a critical reappraisal of the existing sources, it explains their fleeting regional prominence via a pluralistic approach to Paulician identity within the complex socio-religious milieus of Armenia and Asia Minor. Exploring their history of schism, persecution, and resistance, it reassesses their relationship with the iconoclast controversy and the changing fortunes of Byzantine-Islamic warfare, shedding new light on their obscure but fascinating transformation from itinerant preachers to militarized insurrectionists.
Renaissance Philosophy in Jewish Garb
The book deals with the coordinates of a oemodernitya as premises of Jewish philosophy in the Renaissance and early modern period.
Design, Gestaltung, Formatività
What do the work processes of a neurosurgeon and a painter have in common? Applying the notions of “Design”, “Gestaltung”, and “Formatività”, this book sheds new light on processes of formation and transformation in the material world we live in. Scholars from the fields of history, philosophy, psychology, media, and cultural studies question established processes of giving form, while artists, designers, engineers, and scientists describe their creative processes. This book provides its readers with an overview of the spectrum of “philosophies of making” and invites them to reflect on their own creative process, its possibilities, and associated responsibilities to the environment, and ultimately to express these in action. There has never been a more urgent need to develop a new relationship between matter and form. • Discussing and expanding the definitions of “Design”, “Gestaltung”, and “Formatività” • Leading international theorists write about the relationship between matter and form • A collection of new texts and first English translation of key texts
