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This reference on the biologic therapy of cancer provides scientific and practical information to both researchers and clinicians involved in the development and application of new cancer treatments. Major sections of the book cover: cytokines; cell transfer therapy; monoclonal antibodies; cancer vaccines; gene therapy; and antiangiogenesis therapy. Each section begins with basic principles and preclinical studies, and proceeds to clinical applications. The clinical chapters present comprehensive analyses of clinical data, emphasizing the indications for treatment and the practical guidelines necessary to safely apply these new approaches.
On the football field, Sean Taylor was feared by opposing teams. Off the field, he was loved by those who knew him best, as well as his many fans. Tragically, Sean was killed in a home invasion gone wrong. However, “Going Full Speed, the Sean Taylor Stories” is not just about being at the wrong place at the wrong time. It's Sean’s father, Pedro “Pete” Taylor's recollection of raising, training, then losing his superstar son. But Sean Taylor was no saint. And in the words of his father, he wants to give readers "the good, the bad and the ugly." Sean Taylor touched many lives. In "Going Full Speed" you'll be touched by stories from family, friends, teammates, coaches, and the owner o...
This text on analysis of Riemannian manifolds is aimed at students who have had a first course in differentiable manifolds.
One of the nation's leading surgeons tells the compelling story of his headline-making experiments--scientific breakthroughs that may revolutionize the treatment of cancer. Haunted by the question "Can the body rid itself of cancer?" Dr. Rosenberg seized upon immunotherapy as the most promising path toward curing the disease and has since achieved worldwide renown for his work. 8 pages of photographs.
Modern life is full of stuff yet bereft of time. An economic sociologist offers an ingenious explanation for why, over the past seventy-five years, Americans have come to prefer consumption to leisure. Productivity has increased steadily since the mid-twentieth century, yet Americans today work roughly as much as they did then: forty hours per week. We have witnessed, during this same period, relentless growth in consumption. This pattern represents a striking departure from the preceding century, when working hours fell precipitously. It also contradicts standard economic theory, which tells us that increasing consumption yields diminishing marginal utility, and empirical research, which sh...
Studying abstract algebra can be an adventure of awe-inspiring discovery. The subject need not be watered down nor should it be presented as if all students will become mathematics instructors. This is a beautiful, profound, and useful field which is part of the shared language of many areas both within and outside of mathematics. To begin this journey of discovery, some experience with mathematical reasoning is beneficial. This text takes a fairly rigorous approach to its subject, and expects the reader to understand and create proofs as well as examples throughout. The book follows a single arc, starting from humble beginnings with arithmetic and high-school algebra, gradually introducing ...
This practical guide to understanding the cranial nerves as the key to our psychological and physical well-being builds on Stephen Porges’s Polyvagal Theory—one of the most important recent developments in human neurobiology. Drawing on more than thirty years of experience as a craniosacral therapist and Rolfer, Stanley Rosenberg explores the crucial role that the vagus nerve plays in determining our psychological and emotional states and explains that a myriad of common psychological and physical symptoms—from anxiety and depression to migraines and back pain—indicates a lack of proper functioning in the vagus nerve. Through a series of easy self-help exercises, the book illustrates...
(Boosey & Hawkes Chamber Music). This step-by-step instructional booklet takes the student from the basics of holding the recorder, breathing and tonguing to notes, rests and counting. The book also progresses from solos to duets to trios.