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Medical and Health Genomics provides concise and evidence-based technical and practical information on the applied and translational aspects of genome sciences and the technologies related to non-clinical medicine and public health. Coverage is based on evolving paradigms of genomic medicine—in particular, the relation to public and population health genomics now being rapidly incorporated in health management and administration, with further implications for clinical population and disease management. - Provides extensive coverage of the emergent field of health genomics and its huge relevance to healthcare management - Presents user-friendly language accompanied by explanatory diagrams, figures, and many references for further study - Covers the applied, but non-clinical, sciences across disease discovery, genetic analysis, genetic screening, and prevention and management - Details the impact of clinical genomics across a diverse array of public and community health issues, and within a variety of global healthcare systems
The fourth edition of this classical reference book can once again be relied upon to present a cohesive and up-to-date exposition of all aspects of human and medical genetics. Human genetics has become one of the main basic sciences in medicine, and molecular genetics is increasingly becoming a major part of this field. This new edition integrates a wealth of new information - mainly describing the influence of the "molecular revolution" - including the principles of epigenetic processes which together create the phenotype of a human being. Other revisions are an improved layout, sub-division into a larger number of chapters, as well as two-colour print throughout for ease of reference, and many of the figures are now in full colour. For graduates and those already working in medical genetics.
Within the framework of clinical internal medicine, they will gain critical knowledge of the many powerful molecular biology-based developments now so rapidly enhancing our understanding of the pathophysiology of disease, improving the feasibility and accuracy of diagnostic testing, and opening novel therapeutic avenues, including gene therapy. Readers will also gain a fuller understanding of the role played by genetic defects in a host of diseases, among them peripheral neuropathies, Alzheimer's disease, arrhythmias, leukemias and lymphomas, cystic fibrosis, hepatitis, HIV, autoimmune disorders, polycystic kidney disease, schizophrenia, affective disorders, alcoholism, Huntington's disease, and many more.
"This brilliant portait of schizophrenia-the most malignant and least understood mental illness-by renowned psychiatrist Jeffrey Lieberman, Chair of Columbia's legendary Psychiatry department, interweaves cultural and scientific history with dramatic patient portraits and clinical experiences to impart a revolutionary message of hope: that for the first time in human history, schizophrenia can not just be effectively treated, but even prevented. Of the many myths and misconceptions that have historically obscured our understanding of schizophrenia, the most pernicious is that there is no effective treatment or cure. The reality couldn't be more different: the truth is that today's treatments...
Down syndrome (DS) is the most common example of neurogenetic aneuploid disorder leading to mental retardation. In most cases, DS results from an extra copy of chromosome 21 (HSA21) producing deregulated gene expression in brain that gives raise to subnormal intellectual functioning. The topic of this volume is of broad interest for the neuroscience community, because it tackles the concept of neurogenomics, that is, how the genome as a whole contributes to a neurodevelopmental cognitive disorders, such as DS, and thus to the development, structure and function of the nervous system. This volume of Progress in Brain Research discusses comparative genomics, gene expression atlases of the brai...
Presents clinical, biochemical, and genetic information concerning those metabolic anomalies grouped under inborn errors of metabolism.
3 cutting-edge books reveal the latest genetic breakthroughs – and their implications for you, your health, and your world These three cutting-edge books reveal how modern genetics has already transformed the world – and will transform it again and again in the coming years. Mobile DNA book thoroughly reviews our current scientific understanding of the significant role that mobile genetic elements play in the evolution and function of genomes and organisms–from plants and animals to humans. Renowned geneticist Haig Kazazian offers an accessible intellectual history of the field’s research strategies and concerns, explaining how advances have opened up new questions, and how new tools...
A significant contribution to professional training, Social Work and Genetics is a guide to social work practice with clients who have genetic problems. Through their rich clinical experiences in genetic counseling, the authors provide a valuable body of knowledge for other professionals who must help individuals and their families cope with the dilemmas occurring as a result of the presence of a possible or real genetic defect or disease. Social work students, practicing social workers, and professionals from various other disciplines will glean an enormous amount of information on basic genetic principles and issues.
The Nobel Prizes is the official yearbook of the Nobel Foundation. This edition provides extensive information about the 2019 laureates: their Nobel Prize lectures and their autobiographies, as well as presentation speeches and background about the Nobel festivities.Published on behalf of the Nobel Foundation.