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Recent advances in stem cell biology, nanotechnology and gene therapy have opened new avenues for therapeutics. The availability of molecular therapeutics that rely on the delivery of DNA, RNA or proteins, harnessing enhanced delivery with nanoparticles, and the regenerative potential of stem cells (adult, embryonic or induced pluripotent stem cells) has had a tremendous impact on translational medicine. The chapters in this book cover a range of strategies for molecular and cellular therapies for human disease, their advantages, and central challenges to their widespread application. Potential solutions to these issues are also discussed in detail. Further, the book addresses numerous advances in the field of molecular therapeutics that will be of interest to the general scientific community. Lastly, the book provides specific examples of disease conditions for which these strategies have been transferred to the clinic. As such, it will be extremely useful for all students, researchers and clinicians working in the field of translational medicine and molecular therapeutics.
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Winner of the Sahitya Akademi Award An award-winning novel that uses both vast panoramic views and lovingly reconstructed detail to provide an unforgettable picture of nineteenth-century Bengal. The Bengal Renaissance and the 1857 uprising form the backdrop to Those Days, a saga of human frailties and strength. The story revolves around the immensely wealthy Singha and Mukherjee families, and the intimacy that grows between them. Ganganarayan Singha's love for Bindubasini, the widowed daughter of the Mukherjees, flounders on the rocks of orthodoxy even as his zamindar father, Ramkamal, finds happiness in the arms of the courtesan, Kamala Sundari. Bimbabati, Ramkamal's wife, is left to cope w...
The 10th edition of the World Directory of Crystallographers and of Other Scientists Employing Crystallographic Methods is a revised and up-to-date edition of the World Directory and contains the current addresses, academic status and research interests of over 8000 scientists in 74 countries. It is produced directly from the regularly updated electronic World Directory database, which is accessible via the World-Wide Web. Full details of the database are given in an Annex to the printed edition.
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