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New Frontiers: Extracellular Vesicles
The field of extracellular vesicles (EVs) has progressed immensely in recent times with evidences highlighting their importance in physiology and pathology. This book entails extensive reflective literature on many subtypes of EVs including exosomes, exomeres, ectosomes, apoptotic vesicles, bacterial EVs and fungal EVs. The book further discusses the biogenesis and secretion of these EVs, detailing the biological pathways and proteins involved. Research investigating the biological functions of EVs is rapidly increasing and the current knowledge around their role in progression of diseases such as cancer, neurodegeneration and metabolic disorders is discussed in multiple chapters. The implic...
I Am the River
During the last desperate days of the Vietnam War, American soldier Israel Broussard is assigned to a secret CIA PSYOP far behind enemy lines meant to drive terror into the heart of the North Vietnamese and end an unwinnable war. When the mission goes sideways, Broussard is plunged into a nightmare that he soon finds he is unable to escape, dragging a remnant of that night in the Laotian wilderness with him no matter how far he runs. Five years later, too damaged to return home and holed up in the slums of Bangkok, where he battles sleep, guilt, and a creeping sense of madness, Broussard discovers that he must journey back to the jungles of Laos in an attempt to set things right and reclaim what is left of his life. A fever dream with a Benzedrine chaser, I Am The River provides a daring, often surreal examination of the Vietnam War and the days after it, burrowing down past the bullets and battlefields to discover the lingering horror of warfare, the human consequences of organized violence, and the lasting effects of trauma on the psyche, and the soul.
T-Cell Subsets and Cytokines Interplay in Infectious Diseases
Presenting a wealth of new data on the interaction among T-cell subsets and cytokines, this book offers a fresh perspective on infectious diseases. It provides useful insights into the nature and treatment of helminthic and mycobacterial infections, with special emphasis on leprosy, leishmaniasis, malaria and trypanosomiasis. The outcome of the host response to infectious agent is seen as depending upon the T-cell subsets activated and the cytokines produced by them and other cells, such as macrophages, B cells and basophils. Experts contributions shed new light on how TH0 cells are preferentially activated and differentiated into TH1 or TH2 subsets; TH1 and TH2 cells and their cytokines induce both protective immune responses and adverse immune reactions to infectious agents; cytokines modulate the response of infectious diseases to chemotherapy; and cytokines, their receptors and antagonist, and anti-cytokine antibodies can be used in therapy. Those working in the fields of immunology, parasitology, microbiology and vaccine development particularly if they are interested in tropical diseases, will find the volume an invaluable source of information.
Handbook on Cerebral Artery Dissection
Leading international experts summarize up-to-date findings on the presentation, diagnosis, pathogenesis and therapy of cerebral artery dissection. Several topics, such as the first animal model of cervical artery dissection, the epidemiology and its association with connective tissue abnormalities in skin and arteries, genetic approaches in the study of risk factors as well as the main etiologies of spontaneous and traumatic cervical artery dissection are discussed. The book also gives an insight into the clinical manifestations of carotid and vertebral artery dissection and to the possibilities and limitations of the main diagnostic tools, ultrasound, CT and MR imaging, and angiography. The last part of the publication presents the prognosis, thrombolysis and antithrombotic therapy of cervical artery dissection and concludes with an overview of intracranical dissection. Specialists in neurology, neuroradiology, neurosurgery, internal medicine as well as general practitioners will find this publication a useful and unique review of the present knowledge and future research directions of this still poorly understood disease.
They Don't Come Home Anymore
"Find a safe place to die. And make sure it is away from the people and away from the sky." Shirley Jackson Award-nominated author T.E. Grau delivers a tale of obsession, alienation, and a teenage girl in search of something beyond the reach of death. But sometimes, when they journey too far, They Don't Come Home Anymore.
Index Medicus
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
The Nameless Dark
The Nameless Dark debuts a major new voice in contemporary Weird fiction. Within these pages, you ll find whispers of the familiar ghosts of the classic pulps--Lovecraft, Bradbury, Smith--blended with Grau s uniquely macabre, witty storytelling, securing his place at the table amid this current Renaissance of literary horror. "
Amphitrvo
Plautus' Amphitruo is the sole specimen of mythological burlesque in ancient comedy to come down to us in nearly complete form. This sex farce delighted Roman audiences and readers for centuries and continues to inspire adaptations to this day. Dr Christenson utilizes recent work in performance criticism in conjunction with traditional philological analysis to provide new insights into the play in performance. The edition aims to recover the essence of Plautine spectacle from the most concrete details of staging to the complex performative dynamics played out among the actors themselves and the actors and the audience. Included in the Introduction is an account of the mythic and dramatic background to Plautus' play as well as of its influence in post-classical drama. Plautus' metres are explained in a manner students will find helpful and instructive. Dr Christenson presents a new text that includes stage directions in English.
