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This publication, in two volumes, includes most of the scientific papers presented at the first meeting of the International Society for the Study of the Origin of Life (lSSOL), held on June 25-28, 1973 in Barcelona, Spain. The first volume contains the invited articles and the second volume the contributed papers, which also appear in the 1974 and 1975 issues, respectively, of the new journal Origins of Life, published by D. Reidel. A relatively large number of meetings on the subject of the origin of life have been held in different places since 1957. In terms of its organization, scope, and number and nationality of participants, the Conference celebrated last year in Barcelona closely followed the three international conferences held earlier in Moscow, U.S.S.R., 1957, Wakulla Springs, U.S.A., 1963, and Pont-a-Mousson, France, 1970. For this reason the first ISSOL meeting was also named the 4th International Conference on the Origin of Life.
The science of nutrition has advanced beyond expectation since Antoine La voisier as early as the 18th century showed that oxygen was necessary to change nutrients in foods to compounds which would become a part of the human body. He was also the first to measure metabolism and to show that oxidation within the body produces heat and energy. In the two hundred years that have elapsed, the essentiality of nitrogen-containing nutrients and of proteins for growth and maintenance of tissue has been established; the ne cessity for carbohydrates and certain types of fat for health has been docu mented; vitamins necessary to prevent deficiency diseases have been identified and isolated; and the requirement of many mineral elements for health has been demonstrated. Further investigations have defined the role of these nutrients in metabolic processes and quantitated their requirements at various stages of development. Additional studies have involved their use in the possible prevention of, and therapy for, disease conditions.
This publication, in two volumes, includes most of the scientific papers presented at the first meeting of the International Society for the Study of the Origin of Life (ISSOL), held on June 25-28, 1973 in Barcelona, Spain. The first volume contains the invited articles and the second volume the contributed papers, which also appear in the 1974 and 1975 issues, respectively, of the new journal Origins of Life, published by D. Reidel. A relatively large number of meetings on the subject of the origin of life have been held in different places since 1957. In terms of its organization, scope, and number and nationality of participants, the Conference celebrated last year in Barcelona closely followed the three international conferences held earlier in Moscow, U.S.S.R., 1957, Wakulla Springs, U.S.A., 1963, and Pont-a-Mousson, France, 1970. For this reason the first ISSOL meeting was also named the Ath International Conference on the Origin of Life.
Transfer RNA in Protein Synthesis is a comprehensive volume focusing on important aspects of codon usage, selection, and discrimination in the genetic code. The many different functions of tRNA and the specialized roles of the corresponding codewords in protein synthesis from initiation through termination are thoroughly discussed. Variations that occur in the initiation process, in reading the genetic code, and in the selection of codons are discussed in detail. The book also examines the role of modified nucleosides in tRNA interactions, tRNA discrimination in aminoacylation, codon discrimination in translation, and selective use of termination codons. Other topics covered include the adap...
Nearly thirty million species of organisms are believed to now live on Earth. In addition to accumulating evidence from classical biology, paleontology and earth science, the recent progress of molecular biology has provided new insights into understanding how present-day organisms have evolved with such tremendous diversity. Molecular biological studies show us that all living forms, including E. coli and human beings, derive from a single ancestor that emerged some 4 billion years ago on Earth. This volume aims to discuss the motifs of organismic evolution from the viewpoints of biogeo-interactions and diversification of the genetic systems. Based on these fundamental understandings, the last section of this volume is devoted to human evolution that includes phylogeny of man as well as evolution of human culture. Such comprehensive discussion will give us a synthesized view of the evolution of life, that is undoubtedly one of the most important problems not only for science but also for human culture in general.
First Published in 2004. Routledge is an imprint of Taylor & Francis, an informa company.
The Enzymes
Praise for the Serial:"Full of interest not only for the molecular biologist - for whom the numerous references will be invaluable - but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell."--British Medical Journal - Provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology - Contributions from leaders in their fields - Abundant references
Motoo Kimura, as founder of the neutral theory, is uniquely placed to write this book. He first proposed the theory in 1968 to explain the unexpectedly high rate of evolutionary change and very large amount of intraspecific variability at the molecular level that had been uncovered by new techniques in molecular biology. The theory - which asserts that the great majority of evolutionary changes at the molecular level are caused not by Darwinian selection but by random drift of selectively neutral mutants - has caused controversy ever since. This book is the first comprehensive treatment of this subject and the author synthesises a wealth of material - ranging from a historical perspective, through recent molecular discoveries, to sophisticated mathematical arguments - all presented in a most lucid manner.
Conteúdo: Hydrolysis: peptide bonds.