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The Human Hippocampus
This book offers a precise description of the anatomy of human hippocampus in view of neurosurgical progress and the wealth of medical imaging methods available. A survey of the current concepts explains the functions of the hippocampus and describes its external and internal vascularisation. Head sections and magnetic resonance images complete this comprehensive view of human hippocampal anatomy. It will be of interest to neuroscientists and, in particular, to neurosurgeons, neuroradiologists and neurologists.
Atlas of Morphology and Functional Anatomy of the Brain
The recent advances in neuroimaging techniques, particularly magnetic re- nance (MR), have greatly improved our knowledge of brain anatomy and related brain function. Morphological and functional investigations of the brain using high-definition MR have made detailed study of the brain possible and provided new data on anatomo-functional correlations. These studies have fuelled the interest in central nervous system imaging by clinicians (n- roradiologists, neurosurgeons, neurologists, neurophysiologists, and psych- trists) as well as biophysicists and bioengineers, who are at work on new and ever more sophisticated acquisition and processing techniques to continue to improve the potential o...
Neuroimaging Part B
Comprised of two separate volumes, Neuroimaging provides a state-of-the-art review of a broad range of neuroimaging techniques applied to both clinical and research settings. The breadth of the methods covered is matched by the depth of description of the theoretical background. Part B covers the application of neuroimaging in both research and clinical settings for the study of anxiety disorders, dementia, depression, schizophrenia, functional somatic syndromes, stroke, and multiple sclerosis using a range of neuroimaging modalities including CT, PET, SPECT, DTI, structural MRI and fMRI. One chapter is devoted to the study of brain development using structural MRI, and one chapter to the st...
The Neuroscience of Hallucinations
Hallucinatory phenomena have held the fascination of science since the dawn of medicine, and the popular imagination from the beginning of recorded history. Their study has become a critical aspect of our knowledge of the brain, making significant strides in recent years with advances in neuroimaging, and has established common ground among what normally are regarded as disparate fields. The Neuroscience of Hallucinations synthesizes the most up-to-date findings on these intriguing auditory, visual, olfactory, gustatory, and somatosensory experiences, from their molecular origins to their cognitive expression. In recognition of the wide audience for this information among the neuroscientific...
Proteomics and Metabolomics in Psychiatry
This publication compiles data generated by proteomics and metabolomics about psychiatric disorders. Leading researchers in these fields review the basic principles of proteomics and metabolomics and propose the new directions to be followed in molecular psychiatry. The chapters divided into two sections - Schizophrenia/Psychotic Disorders and Mood Disorders - deal with findings in diverse tissues from human and preclinical models in order to unravel the biology and biochemistry behind the establishment and course of these illnesses as well as potential biomarkers for clinical applications. More than an update, this publication indicates the next steps to discover biomarkers and understand psychiatric disorders more comprehensively. This publication is valuable reading for psychiatrists, neuroscientists and analytical chemists interested in the basics of proteomics and metabolomics, psychiatric definitions and the most advanced hypotheses about the pathobiology of schizophrenia, depression and bipolar disorder.
Autism
The book covers some of the key research developments in autism and brings together the current state of evidence on the neurobiologic understanding of this intriguing disorder. The pathogenetic mechanisms are explored by contributors from diverse perspectives including genetics, neuroimaging, neuroanatomy, neurophysiology, neurochemistry, neuroimmunology, neuroendocrinology, functional organization of the brain and clinical applications from the role of diet to vaccines. It is hoped that understanding these interconnected neurobiological systems, the programming of which is genetically modulated during neurodevelopment and mediated through a range of neuropeptides and interacting neurotrans...
Advanced MR Neuroimaging
Over the last decade, some of the greatest achievements in the field of neuroimaging have been related to remarkable advances in magnetic resonance techniques, including diffusion, perfusion, magnetic resonance spectroscopy, and functional MRI. Such techniques have provided valuable insights into tissue microstructure, microvasculature, metabolism and brain connectivity. Previously available mostly in research environments, these techniques are now becoming part of everyday clinical practice in a plethora of clinical MR systems. Nevertheless, despite growing interest and wider acceptance, there remains a lack of a comprehensive body of knowledge on the subject, exploring the intrinsic comple...
Neuroimaging in Forensic Psychiatry
As neuroimaging becomes more widespread, it is increasingly being used in the courts, even though understanding and interpreting neuroimaging methods and results can be very challenging – even without attempting to evaluate their potential applications to forensic questions. The sheer volume of available information, research results, and opinions can seem intimidating to forensic practitioners and to mental health professionals in general. This will be the first book dedicated to this important topic. Designed as a reference for forensic psychiatrists, it starts with a brief overview of the psychiatric applications of the primary neuroimaging techniques currently in most widespread use, p...
Data Mining for Biomarker Discovery
Biomarker discovery is an important area of biomedical research that may lead to significant breakthroughs in disease analysis and targeted therapy. Biomarkers are biological entities whose alterations are measurable and are characteristic of a particular biological condition. Discovering, managing, and interpreting knowledge of new biomarkers are challenging and attractive problems in the emerging field of biomedical informatics. This volume is a collection of state-of-the-art research into the application of data mining to the discovery and analysis of new biomarkers. Presenting new results, models and algorithms, the included contributions focus on biomarker data integration, information retrieval methods, and statistical machine learning techniques. This volume is intended for students, and researchers in bioinformatics, proteomics, and genomics, as well engineers and applied scientists interested in the interdisciplinary application of data mining techniques.
