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Osteosarcoma
This book reviews the brilliant progress made in the past three decades in clinical outcomes for osteosarcoma patients treated with a multidisciplinary approach, including limb-salvage surgery combined with neoadjuvant multidrug chemotherapy and aggressive management of pulmonary metastasis. Osteosarcoma was a miserable disease for adolescents and young adults until the early 1970s, with a survival rate that was less than 10–15% even after amputation for affected limbs because of the progression of pulmonary metastasis. With the development of neoadjuvant chemotherapy for osteosarcoma, including high-dose methotrexate, doxorubicin, cisplatin, and ifosfamide during the late 1970s and the 19...
Suicide Risk Assessment and Prevention
This book explores suicide prevention perspectives from around the world, considering both professionals’ points of view as well as first-person accounts from suicidal individuals. Scholars around the globe have puzzled over what makes a person suicidal and what is in the minds of those individuals who die by suicide. Most often the focus is not on the motives for suicide, nor on the phenomenology of this act, but on what is found from small cohorts of suicidal individuals. This book offers a tentative synthesis of a complex phenomenon, and sheds some light on models of suicide that are less frequently encountered in the literature. Written by international experts, it makes a valuable contribution to the field of suicidology that appeals to a wide readership, from mental health professionals to researchers in suicidology and students.
Introduction to Translational Cardiovascular Research
The term “Translational Research” reflects today’s integration of basic research (“bench”) findings with the clinical practice of medicine, and in a wider scope the application of results from the individual patient (“bedside”) to entire populations for the improvement of public health. This book offers future researchers a stimulus in many aspects of cardiovascular research, so as to promote their interest in future fields of cardiovascular disease, diagnosis and treatment. Introduction to Translational Cardiovascular Research discusses the fundamental and important aspects of the topic. It describes the renin-angiotensin-aldosterone system, the beta adrenergic receptors and t...
The Proceedings of the 2021 Asia-Pacific International Symposium on Aerospace Technology (APISAT 2021), Volume 1
This proceeding comprises peer-reviewed papers of the 2021 Asia-Pacific International Symposium on Aerospace Technology (APISAT 2021), held from 15-17 November 2021 in Jeju, South Korea. This book deals with various themes on computational fluid dynamics, wind tunnel testing, flow visualization, UAV design, flight simulation, satellite attitude control, aeroelasticity and control, combustion analysis, fuel injection, cooling systems, spacecraft propulsion and so forth. So, this book can be very helpful not only for the researchers of universities and academic institutes, but also for the industry engineers who are interested in the current and future advanced topics in aerospace technology.
Chemical kinetics
The volume is devoted to the problem of chemical kinetics on modern level. The book includes information on chemical physics of nanocomposites, degradation, stabilization and flammability of polymeric materials as well as free radical mechanism of oxidation of organic compounds, thermostability, mechanism of action of catalytical systems and inhibi
Assessment of Immune status by the Leukocyte Adherence Inhibition Test
Assessment of Immune Status by the Leukocyte Adherence Inhibition Test reviews many aspects of the immune response and cellular requirements in leukocyte adherence inhibition (LAI). It compares the LAI methodology with alternative approaches, discusses the method that has been adopted to determine whether the LAI phenomenon measures a specific immune response, and explores how these phenomena fit in with and relate to the traditional immune response. Organized into three parts encompassing 15 chapters, this volume begins with an overview of the hemocytometer assay, the immunological basis and applications of hemocytometer LAI, the immune response as assayed by the test tube method, and the m...
In-situ Studies with Photons, Neutrons and Electrons Scattering II
This book provides an insight into current research topics, focusing special attention exactly on welding issues. The presented research work demonstrates that application of synchrotron and neutron radiation in combination with other techniques enables the basic understanding of material-related processes to be extended appreciably. It also shows ways of how to improve new materials and their use in industry. Following on from the 1st workshop in 2009 at BAM Berlin, a 2nd workshop dealing with this subject matter was held in 28-30 November, 2012 in Osaka/Japan with international participation of scientists from sixteen countries. The book includes selected contributions from the various subject blocks, precisely covering issues of practical and immediately implementable benefit to industrial enterprises. Therefore, peer-reviewed papers dealing with the following topics are contained as well: - Phase transformation during welding, metallurgy and material development - Evolution and significance of residual stresses - Investigations into laser and electron beam welding
The Chemistry of Rotational Isomers
Rotation about the Carbon-Carbon single bond is generally regarded to be unrestricted. About 50 years ago, rotational isomers were found to exhibit optical activity: substituted biphenyl derivatives. However, the author has investigated other classes of compounds that have stable rotational isomers at room temperature. These compounds can serve as models for studying very weak intermolecular interactions, that are difficult to observe. Even diastereotopic groups show different chemical reactivity. From the contents: The "Free Rotation Concept" - Rotamer Populations - Barriers to Rotation - Reactivity of Rotational Isomers.
Handbook of Radio and Optical Networks Convergence
This handbook provides comprehensive knowledge on device and system technologies for seamlessly integrated networks of various types of transmission media such as optical fibers and millimeter and THz waves to offer super high-speed data link service everywhere. The seamless integration of the knowledge of radio and optical technologies is needed to construct wired and wireless seamless networks. High-frequency bands such as millimeter-wave and THz-wave bands where super wideband spectra are available can offer high-speed data transmission and high-resolution sensing. However, the expected coverage is limited due to large wave propagation loss. Thus, convergence of radio and optical links is...
