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Glycans are complex, multi-unit carbohydrate structures that cover the surfaces of cells and guide cellular interactions. Glycobiology studies the synthesis, structure, function, regulation, and evolution of glycans and glycan-binding molecules. Glycans are synthesized and added as modifications to proteins, lipids, and RNA. Though they are often associated with functions outside of cells (glycoproteins and glycolipids are most often extracellular or secreted), glycans are also active within cells. Glycans are known to have diverse physiological roles ranging from cell adhesion (maintaining tissue structure and integrity) to molecular recognition (marking position during development, or self-identity in immunity and reproduction). Glycans also regulate cellular activity and physiological state. The families of proteins that bind glycans are called lectins. Glycans and lectins are vital in many diseases such as cancer, neurodegeneration, inflammation, allergies, asthma, and autoimmune disorders.
Rapid or even dramatic progress has been made in the field of AMD over recent years, leading to a constant revision of basic concepts. A wide range of fundus imaging modalities are now available, and this book explains the respective value of each technique. The information provided by OCT is presented logically by comparison with plain films, autofluorescence, fluorescein angiography, or indocyanine green angiography. Meticulous biomicroscopic examination of macular changes and the essential value of fluorescein angiography for the detection of anatomical alterations of the macula and for precise evaluation of lesions and their course by indocyanine green angiography have naturally led the author Gabriel Coscas to analyze the new data provided by OCT.
This Book of Abstracts is the main publication of the 71st Annual Meeting of the European Federation of Animal Science (EAAP). It contains abstracts of the invited papers and contributed presentations of the sessions of EAAP's eleven Commissions: Animal Genetics, Animal Nutrition, Animal Management and Health, Animal Physiology, Cattle Production, Sheep and Goat Production, Pig Production, Horse Production and Livestock Farming Systems, Insects and Precision Livestock Farming.
Fatty acids are considered as a very important category of chemical compounds to human health as well as from an industrial perspective. This book intends to provide an update on fatty acid research, their methods of detection, quantification, and related diseases such as cardiovascular disease and diabetes. Cyclic fatty acids are also covered, along with short chain fatty acids, which are important to the human gut microbiota. Fatty acids are important in the chemical structure of the cell membrane and its pivotal role in this aspect is reviewed herein. The book also contains a chapter that deals with some unpublished molecular aspects concerning the roles of fatty acids in depression and bipolar disorder. All in all, the book provides a brief overview of both highly explored as well as overlooked perspectives of fatty acids, while highlighting its significance as a biochemical molecule, which is imperative to the livelihood of unicellular and multi-cellular organisms alike.
"This sourcebook is intended to assist environmental managers and others who work with indicators in pursuing appropriate methods for indicator testing and production, and to offer some guidance to those responsible for the interpretation of indicators and implementation of decisions based on them. Upon reading this document, technical advisers, environmental policy makers, and remote sensing lab directors and project managers should be able to identify specific, relevant uses of remote sensing data for biodiversity monitoring and indicator development related to the CBD." --p. 8.
This new edition updated the material by expanding coverage of certain topics, adding new examples and problems, removing outdated material, and adding a computer disk, which will be included with each book. Professor Jaluria and Torrance have structured a text addressing both finite difference and finite element methods, comparing a number of applicable methods.
The last 30 years has seen the development of increasingly sophisticated models that quantify canopy carbon exchange. These models are now essential parts of larger models for prediction and simulation of crop production, climate change, and regional and global carbon dynamics. There is thus an urgent need for increasing expertise in developing, use and understanding of these models. This in turn calls for an advanced, yet easily accessible textbook that summarizes the “canopy science” and introduces the present and the future scientists to the theoretical background of the current canopy models. This book presents current knowledge of functioning of plant canopies, models and strategies employed to simulate canopy function, and the significance of canopy architecture, physiology and dynamics in ecosystems, landscape and biosphere.
This text provides expert instruction on the varying surgical techniques currently employed for the regeneration of the ocular surface. Corneal Regeneration: Therapy and Surgery begins with a thorough discussion of current research based on data obtained in clinical human studies, and discusses the potential clinical implications for this promising new stage of eye surgery. Sections devoted to the stem cell, regenerative surgery and therapy of the ocular surface epithelium, corneal stroma, and corneal endothelium follow, each section comprehensively covering applied anatomy, current therapy and regenerative techniques, with a look to future directions of the field including eventual cell therapy. Corneal Regeneration: Therapy and Surgery is the first book of its kind, systematically covering the developments the medical community has achieved in corneal regeneration from all angles. Written and edited by leading experts in the field, researchers and ophthalmologists alike will find this to be a unique source of information on corneal regeneration, as well as a thoughtful reflection on potential applications of regenerative surgery in ophthalmology as a whole.