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How Tobacco Smoke Causes Disease
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Law Without Values
Albert Alschuler's study of Holmes is very different from other books about him, in that it is an exercise in debunking him.
Pattern Design
Throughout history, patterns have come in countless permutations of motif, colour-way and scale. Yet what all have in common is the regularity of repetition, that insistent rhythm that animates a flat surface with a sense of movement and vitality and gives it depth. Evident in the arrangement of petals on a flower head, the branching growth of stems and vines, the spirals of a seashell - pattern is inherent in the natural world that surrounds us. Powerful and transformative, pattern has an irrepressible joie de vivre. With more than 1,500 illustrations of patterns from all ages and cultures, Pattern Design is a visual feast. This comprehensive compendium is arranged thematically according to type, with chapters on Flora, Fauna, Pictorial, Geometric and Abstract designs. These broad categories are supplemented by in-depth features highlighting the work of key designers from the rich history of pattern-making - such as William Morris, Sonia Delaunay, Charles and Ray Eames, Lucienne Day and Orla Kiely - along with sections detailing the characteristic motifs of key period styles from Baroque to Art Deco.
Lloyd's Register of Shipping 1850
The Lloyd's Register of Shipping records the details of merchant vessels over 100 gross tonnes, which are self-propelled and sea-going, regardless of classification. Before the time, only those vessels classed by Lloyd's Register were listed. Vessels are listed alphabetically by their current name.
Warfare in a Fragile World
"Among the crucial problems that confront mankind today are those associated with a degraded environment. This book examines the extent to which warfare and other military activities contribute to such degradation. The military capability to damage the environment and to cause ecological disruption has escalated, and there is no sign that the level of conflict in the world is decreasing. The military use and abuse of each of the several major global habitats -- temperate, tropical, desert, arctic, insular, and oceanic -- are evalusated separately in the light of the civil use and abuse of that habitat"--Dust jacket.
Guide to the Draper Manuscripts
In the mid-nineteenth century the Wisconsin Historical Society's first director, Lyman C. Draper, gathered outstanding materials such as the Daniel Boone papers, which include Draper's interviews with Boone's son, and the papers of Revolutionary War hero George Rogers Clark. These two collections alone are of vast significance to frontier history before 1830, but the full collection comprises nearly five hundred volumes of records, including military and government records, interviews, Draper's own research notes, and rare personal letters. For scholars, genealogists, and local historians, the Draper papers offer a wealth of information on the social, economic, and cultural conditions experienced by our frontier forebears. The 180-page index lists thousands of names and is an indispensable guide for all who wish to use the collection, which is available in libraries across the country on microfilm.
Diet and Health
Diet and Health examines the many complex issues concerning diet and its role in increasing or decreasing the risk of chronic disease. It proposes dietary recommendations for reducing the risk of the major diseases and causes of death today: atherosclerotic cardiovascular diseases (including heart attack and stroke), cancer, high blood pressure, obesity, osteoporosis, diabetes mellitus, liver disease, and dental caries.
The Coronaviridae
Coronaviruses were recognized as a group of enveloped, RNA viruses in 1968 and accepted by the International Committee on the Taxonomy of Viruses as a separate family, the Coronaviridae, in 1975. By 1978, it had become evident that the coronavirus genomic RNA was infectious (i. e. , positive strand), and by 1983, at least the framework of the coronavirus replication strategy had been per ceived. Subsequently, with the application of recombinant DNA techniques, there have been remarkable advances in our understanding of the molecular biology of coronaviruses, and a mass of structural data concerning coronavirus genomes, mRNAs, and pro teins now exists. More recently, attention has been focuse...
