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Lipid-Mediated Signaling
As the highly anticipated update to Lipid Second Messengers (CRC Press, 1999), Lipid-Mediating Signaling is a current and comprehensive overview of research methods used in lipid-mediated signal transduction. Pioneering experts provide a much-needed distillation of a decade's worth of advances in research techniques that are pertinent in understand
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Lipid-Mediated Signaling Transduction, Second Edition
This volume is an extension of the subjects covered in the first edition. There are 5 sections each with 4 to 7 chapters. The 1st and 5th sections will present advances in techniques for study of mammalian lipids over the past 6-7 years since the 1st edition was assembled. The 2nd and 3rd section concerning analysis of plant lipids and signaling are novel and will describe methodology not available elsewhere. Of practical interest will be the chapter outlining approaches to modify lipid production. The 4th section that deals with the impact of bioactive lipids on receptor function will be complementary to the extensive knowledge of lipid-mediated signaling pathways.
Handbook of Essential Fatty Acid Biology
Internationally eminent scientists illuminate the most important scientific aspects of essential fatty acids (EFAs)-from their biochemistry to their physiological consequences in both health and illness. The distinguished contributors integrate a wide range of topics, including the basic biochemistry of EFAs and lipid metabolism, the role of EFAs in the neuronal membrane, the effects of EFAs and lipids in various diseases, and the effects of normal levels and EFA deficiencies on cognition and behavior. The book's consolidation of our knowledge of the biology and metabolism of the EFAs lays the groundwork for dramatic advances in our understanding of these ubiquitous biochemicals and their role in health and illness.
Epigenetic Mechanisms in Neural Plasticity
Neural plasticity is a unique and adaptive feature of nervous system, which allows neurons to reorganize their interactions in response to a stimulation (intrinsic or extrinsic) to maintain their function. For these reasons, epigenetics emerges as a potential field for developing strategies to modulate changes in pathological situation because extrinsic factors and pharmacological tools can modify neural functioning in organisms during their life. Diet, exercise, environmental aspects, stressors or drugs are available to alter those mechanisms. Epigenetic involves certain molecular signaling pathways, as DNA methylation and histone acetylation and deacetylation, and the emerging non-coding s...
Lung Biology and Pathophysiology
The lungs are the organ for gas exchange between the body and the external environment. Dysfunction of upper airway epithelium and smooth muscle cells leads to pathogenesis of asthma, chronic obstructive pulmonary disease (COPD), cystic fibrosis, and other conditions, resulting in airway inflammation and narrowing. Injury to alveolar epithelium and endothelium causes influx of neutrophil and protein-rich fluid from circulation, resulting in edema and disruption of gas exchange. In addition to lung structural cells, immune cells, including alveolar macrophages and lymphocytes play critical roles in the maintenance of lung function. This book contributes to the understanding homeostasis of lun...
TRP Channels
The rapid expansion of the TRP field has generated a large amount of excellent original work across many different research fields. However, investigators are not necessarily familiar with the pros and cons of the variety of methods used to study TRP channels. Because of functional and genetic diversity, as well as the different physiological roles
