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Racing for the Surface
  • Language: en
  • Pages: 648

Racing for the Surface

This book covers the latest research in biofilm, infection, and antimicrobial strategies in reducing and treating musculoskeletal, skin, transfusion, implant-related infections, etc. Topics covered include biofilms, small colony variants, antimicrobial biomaterials (antibiotics, antimicrobial peptides, hydrogels, bioinspired interfaces, immunotherapeutic approaches, and more), antimicrobial coatings, engineering and 3D printing, antimicrobial delivery vehicles, and perspectives on clinical impacts. Antibiotic resistance, which shifts the race toward bacteria, and strategies to reduce antibiotic resistance, are also briefly touched on. Combined with its companion volume, Racing for the Surface: Pathogenesis of Implant Infection and Advanced Antimicrobial Strategies, this book bridges the gaps between infection and tissue engineering, and is an ideal book for academic researchers, clinicians, industrial engineers and scientists, governmental representatives in national laboratories, and advanced undergraduate students and post-doctoral fellows who are interested in infection, microbiology, and biomaterials and devices.

Biomaterials Associated Infection
  • Language: en
  • Pages: 564

Biomaterials Associated Infection

Biomaterials associated infection (BAI) is one of the most common complications associated with implantation of any biomaterial regardless of form or function. These infections usually involve bacterial colonization and biofilm formation on the biomaterial itself, rendering the infection impervious to antimicrobials and host defenses. In addition, it is becoming increasingly clear that infection of the surrounding tissues also plays an important role in BAI, and that the infection may be influenced by the composition and design of the implanted biomaterial. In this book, worldwide leaders in the field address this critical problem in the translation of biomaterials research into clinical pra...

Perspectives of Quorum Quenching in New Drug Development
  • Language: en
  • Pages: 207

Perspectives of Quorum Quenching in New Drug Development

  • Type: Book
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  • Published: 2024-05-09
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  • Publisher: CRC Press

Antibiotic resistance in pathogen microorganisms is a major global concern, especially the formation of biofilms. Quorum quenching has been practically used to control biofilm growth, and this indicates a promising hope for the development of new drugs for the control of biofilm-forming pathogens. This book provides a single source of information about two issues: the biology of quorum sensing and quorum quenching, and the perspectives of quorum quenching in new drug development. The text covers the latest literature from the last ten years and insights into quorum quenching and its need in medicine as an anti-virulence strategy. Features: Exclusively focuses on quorum quenching and its abil...

Antibiotic Alternatives and Combinational Therapies for Bacterial Infections
  • Language: en
  • Pages: 222

Antibiotic Alternatives and Combinational Therapies for Bacterial Infections

The thoughtless person playing with penicillin treatment is morally responsible for the death of the man who succumbs to infection with the penicillin-resistant organism.” As Alexander Fleming predicted already in 1945 bacteria have become resistant to antibiotics. From time to time we are bombarded with news of infections and deaths caused by antibiotic resistant and multiple drug resistant superbugs. This increase of resistance towards commonly used antibiotics due to decades of use, misuse and abuse of antibiotics, is today a global health concern. Research investments on development of new antimicrobials that can fight antimicrobial resistant microorganisms are scarce yet some new anti...

Women in Cytokines and Soluble Mediators in Immunity
  • Language: en
  • Pages: 848

Women in Cytokines and Soluble Mediators in Immunity

We are delighted to present the inaugural Frontiers in Immunology “Women in Cytokines and Soluble Mediators in Immunity” series of article collections. At present, less than 30% of researchers worldwide are women. Long-standing biases and gender stereotypes are discouraging girls and women away from science-related fields, and Science, Technology, Engineering and Mathematics (STEM) research in particular. Science and gender equality are, however, essential to ensure sustainable development as highlighted by UNESCO. In order to change traditional mindsets, gender equality must be promoted, stereotypes defeated, and girls and women should be encouraged to pursue STEM careers.

Impact of Microbiome on Gut Mucosal Immunity in Health and Disease
  • Language: en
  • Pages: 249
Nanotechnology for Antimicrobials
  • Language: en
  • Pages: 170

Nanotechnology for Antimicrobials

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

PEEK Biomaterials Handbook
  • Language: en
  • Pages: 309

PEEK Biomaterials Handbook

PEEK biomaterials are currently used in thousands of spinal fusion patients around the world every year. Durability, biocompatibility and excellent resistance to aggressive sterilization procedures make PEEK a polymer of choice, replacing metal in orthopedic implants, from spinal implants and hip replacements to finger joints and dental implants. This Handbook brings together experts in many different facets related to PEEK clinical performance as well as in the areas of materials science, tribology, and biology to provide a complete reference for specialists in the field of plastics, biomaterials, medical device design and surgical applications. Steven Kurtz, author of the well respected UH...

Bone and Joint Infections
  • Language: en
  • Pages: 429

Bone and Joint Infections

Infections of the bones (osteomyelitis) and joints (septic arthritis) are serious health problems which require antibiotics and often surgery. Awareness among health professionals of the causes and treatment options for various types of bone and joint infections is essential for effective resolution. Bone and Joint Infections takes a multidisciplinary approach in covering the diagnostic and therapeutic treatment of osteomyelitis and septic arthritis, including different types of implant-associated infections. Correct and rapid diagnosis of bone and joint infection is crucial, and requires the input of a variety of specialists. Bone and Joint Infection takes a similarly collaborative and comprehensive approach, including chapters authored by clinicians, laboratory specialists, and surgeons. Covering the basic microbiology and clinical aspects of bone and joint infection, this book will be a valuable resource both for researchers in the lab and for physicians and surgeons seeking a comprehensive reference on osteomyelitis and septic arthritis.