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Racing for the Surface
This book covers the latest research in biofilm, infection, and antimicrobial strategies in reducing and treating musculoskeletal, skin, transfusion, implant-related infections, etc. Topics covered include biofilms, small colony variants, antimicrobial biomaterials (antibiotics, antimicrobial peptides, hydrogels, bioinspired interfaces, immunotherapeutic approaches, and more), antimicrobial coatings, engineering and 3D printing, antimicrobial delivery vehicles, and perspectives on clinical impacts. Antibiotic resistance, which shifts the race toward bacteria, and strategies to reduce antibiotic resistance, are also briefly touched on. Combined with its companion volume, Racing for the Surface: Pathogenesis of Implant Infection and Advanced Antimicrobial Strategies, this book bridges the gaps between infection and tissue engineering, and is an ideal book for academic researchers, clinicians, industrial engineers and scientists, governmental representatives in national laboratories, and advanced undergraduate students and post-doctoral fellows who are interested in infection, microbiology, and biomaterials and devices.
Racing for the Surface
This book covers the key basics of tissue engineering as well as the latest advances in the integration of both antimicrobial and osteoinductive properties. Topics covered include osteoconductive and osteoinductive biomaterials (calcium phosphate, bone morphogenetic protein, peptides, antibodies, bioactive glasses, nanomaterials, etc.) and scaffolds. Research integrating both antimicrobial/biofilm-inhibiting and osteoinductive/osteoconductive properties and their co-delivery is detailed and their roles in clinical success are discussed. Combined with its companion volume, Racing for the Surface: Antimicrobial and Interface Tissue Engineering, this book bridges the gap between infection and tissue engineering, and is an ideal book for academic researchers, clinicians, industrial engineers and scientists, governmental representatives in national laboratories, and advanced undergraduate students and post-doctoral fellows who are interested in tissue engineering and regeneration, infection, and biomaterials and devices.
Biomaterials Associated Infection
Biomaterials associated infection (BAI) is one of the most common complications associated with implantation of any biomaterial regardless of form or function. These infections usually involve bacterial colonization and biofilm formation on the biomaterial itself, rendering the infection impervious to antimicrobials and host defenses. In addition, it is becoming increasingly clear that infection of the surrounding tissues also plays an important role in BAI, and that the infection may be influenced by the composition and design of the implanted biomaterial. In this book, worldwide leaders in the field address this critical problem in the translation of biomaterials research into clinical pra...
Perspectives of Quorum Quenching in New Drug Development
Antibiotic resistance in pathogen microorganisms is a major global concern, especially the formation of biofilms. Quorum quenching has been practically used to control biofilm growth, and this indicates a promising hope for the development of new drugs for the control of biofilm-forming pathogens. This book provides a single source of information about two issues: the biology of quorum sensing and quorum quenching, and the perspectives of quorum quenching in new drug development. The text covers the latest literature from the last ten years and insights into quorum quenching and its need in medicine as an anti-virulence strategy. Features: Exclusively focuses on quorum quenching and its abil...
Bone and Joint Infections
Infections of the bones (osteomyelitis) and joints (septic arthritis) are serious health problems which require antibiotics and often surgery. Awareness among health professionals of the causes and treatment options for various types of bone and joint infections is essential for effective resolution. Bone and Joint Infections takes a multidisciplinary approach in covering the diagnostic and therapeutic treatment of osteomyelitis and septic arthritis, including different types of implant-associated infections. Correct and rapid diagnosis of bone and joint infection is crucial, and requires the input of a variety of specialists. Bone and Joint Infection takes a similarly collaborative and comprehensive approach, including chapters authored by clinicians, laboratory specialists, and surgeons. Covering the basic microbiology and clinical aspects of bone and joint infection, this book will be a valuable resource both for researchers in the lab and for physicians and surgeons seeking a comprehensive reference on osteomyelitis and septic arthritis.
Principles of Orthopedic Infection Management
The medical world continues to make extraordinary advances in both scientific knowledge and surgical skill, yet despite these achievements, surgeons continue to struggle with the challenge of postoperative infection. Without proper prevention or treatment, orthopedic infection can become just as life-threatening as the initial trauma. This highly informative clinical go-to text provides the core principles, treatment options, and the latest information and research specifically for the purpose of helping physicians manage orthopedic infections and related issues. The book's key features include: Contributions from 63 world renowned specialists from a broad range of fields in orthopedic traum...
Apley and Solomon’s Concise System of Orthopaedics and Trauma
Apley & Solomon's Concise System of Orthopaedics and Trauma is firmly established as the leading introductory textbook of orthopaedic practice and the principles of fracture and trauma management. Praised in previous editions for the systematic approach, balanced content and easy-to-read style, this fifth edition has been brought fully up to date under the direction of the new and distinguished authorial team, while remaining true to the teaching principles of Alan Apley and his successor Louis Solomon. Key features: Focused – on diseases and clinical signs with additional detail on anatomy where appropriate International – enhanced coverage of 'global orthopaedics' reflect the changing ...
Dreamtime
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Introducing John Moriarty in His Own Words
In Introducing Moriarty Canadian theologian and academic Michael W. Higgins compiles the essential writings of Irish philosopher and mystic, John Moriarty. This distillation of Moriarty's texts on ecology, mysticism and spirituality is a perfect introduction to the work of this complex and, at times, esoteric philosopher. Higgins' commentary provides an excellent guide to one of the country's most enigmatic modern thinkers and is an essential addition to the library of anyone interested in Irish philosophy and spirituality.
