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Biochemistry: The Chemical Reactions of Living Cells is a 16-chapter reference source on chemical structures and reactions of living cells. The first three chapters of this book contain introductory material on cell structure, molecular architecture, and energetic. The subsequent chapters examine the allosteric effect of the binding structures of oligomeric enzymes, microtubules, viruses, and muscle. These chapters also describe the structures and chemical properties of membranes and of the surrounding cell coats. The discussions then shift to the general properties of enzymes, the kinetics of chemical reactions, and the various mechanisms employed in enzymatic catalysis. Considerable chapters are devoted to the reaction sequences found in metabolism. These chapters particularly examine the carbohydrate and lipid metabolism; photosynthesis; and biosynthesis and catabolism of an enormous number of nitrogenous compounds. The final chapters highlight the genetic and hormonal control of metabolism, development, and brain function. Biochemistry teachers and students will find this book of great value.
A comprehensive guide to privileged structures and their application in the discovery of new drugs The use of privileged structures is a viable strategy in the discovery of new medicines at the lead optimization stages of the drug discovery process. Privileged Structures in Drug Discovery offers a comprehensive text that reviews privileged structures from the point of view of medicinal chemistry and contains the synthetic routes to these structures. In this text, the author—a noted expert in the field—includes an historical perspective on the topic, presents a practical compendium to privileged structures, and offers an informed perspective on the future direction for the field. The book...
This work presents a definitive interpretation of the current status of and future trends in natural products—a dynamic field at the intersection of chemistry and biology concerned with isolation, identification, structure elucidation, and chemical characteristics of naturally occurring compounds such as pheromones, carbohydrates, nucleic acids, and enzymes. With more than 1,800 color figures, Comprehensive Natural Products II features 100% new material and complements rather than replaces the original work (©1999). Reviews the accumulated efforts of chemical and biological research to understand living organisms and their distinctive effects on health and medicine Stimulates new ideas am...
This book chronologically analyzes fourteen key US Presidents, from Washington to Biden, to highlight how religion has informed or influenced their politics and policies. For years, leading scholars have largely neglected religion in presidential studies. Yet, religion has played a significant role in a number of critical presidencies in US history. This volume reveals the deep religious side to such presidents as Truman, Eisenhower, and Reagan, among others, and the impact that faith had on their administrations. Now in its fourth edition, this work includes analysis of Joe Biden as the second Catholic president in United States history and provides a timely update to a key text in the study of religion and the presidency.
Biological Electrochemistry, Volume I is a result of a series of lectures given regarding the electrochemistry of small and large organic and inorganic molecules and how electrochemical information helps in understanding some of the biological redox reactions of these systems. This volume ultimately focuses on the electrochemistry of small and macromolecular organic compounds. This book is divided into seven chapters where each focuses on a particular organic compound. These compounds are quinones, catecholamines, phenothiazines, ascorbic acid, purines, vitamin B12 and related compounds, and proteins. Each chapter starts with a brief introduction to the compounds and then its structure and electrochemistry aspect. The last chapter gives a detailed discussion on different kinds of proteins and their electrochemistry aspects. This volume will be of help to students as well as electrochemists, biochemists, biologists, and other scientists in the field of biotechnology.
A unique, rigorous scientific approach to understanding bacterial genetics • Provides a complete overview of the entire field of bacterial genetics, helping the reader to understand how the field has evolved. • Inspires readers by providing an opportunity to learn from John Roth’s achievements and contributions to bacterial genetics. • Offers valuable lessons in the history and science of bacterial genetics by providing a behind the scenes look at some of the most important triumphs and mishaps that have occurred on the path to discovery.
Volume 37 of "Progress in Drug Research" contains seven articles and the various indexes which facilitate its use and establish the connection with the previous volumes. While all articles deal with some of the topical aspects of drug research, the contribution by Al fred Burger on "Isosterism and bioisosterism in drug design" is of great value to those researchers who are engaged in drug design and wish to include isosteric considerations in establishing a work ing hypothesis. The remaining six reviews provide an overview of the work in volved in the search for new and better medicines. All these articles contain surveys of the latest findings in the respective domain. In the 31 years this series has existed, the Editor has enjoyed the help and advise of many colleagues. Readers, the authors of the in dividual reviews and, last but 'not least, the reviewers have all con tributed greatly to the success of PDR. Although many comments received have been favorable, it is nevertheless also necessary to an alyze and to reconsider the current position and the direction of such a series.
This book is an introduction to quality initiative for vascular surgery and medicine. Originally published in German, the book is written by leading experts who utilise their professional expertise and insight to help raise the level of patient safety, quality of care, and training of junior vascular physicians. This books aims to bring together the best available current treatment and information, including recent guidelines, meta-analyses, and randomised trials to help put evidence-based therapeutic recommendations into practice. Innovative therapeutic treatment options are not currently incorporated within standard procedure, and this book will help physicians include these methods and create more individualised treatment.
Pick up The New York Public Library Literature Companion to check the dates of Marcel Proust's Remembrance of Things Past or to find out how James Joyce's Ulysses changed U.S. obscenity laws, and you may find yourself hours later absorbed in the imaginary worlds of Camelot and The Matrix or sidetracked by the fascinating history of The New Yorker. Designed to satisfy the curious browser as well as the serious researcher, this exciting new resource offers the most up-to-date information on literature available in English from around the world, from the invention of writing to the age of the computer. Interwoven throughout the more than 2,500 succinct and insightful entries on Creators, Works ...
Metabolic Inhibitors: A Comprehensive Treatise, Volume IV reviews developments in studies of inhibition of metabolic and enzymic processes ranging from photosynthesis and blood clotting to protein synthesis, fatty acid metabolism, and phospholipid metabolism. The book also explores the inhibition of specific enzyme reactions, such as amino acid activation, amino acid hydroxylation, and cyclic AMP formation. Organized into nine chapters, this volume begins with an overview of allosteric inhibition and inhibitors, and then discusses amino acid hydroxylase inhibitors. The reader is also introduced to inhibitors and activators of enzymes that regulate the cellular concentration of cyclic AMP. In particular, the book describes the role of lipids in the activation of adenyl cyclase by hormones; modification of adenyl cyclase in various physiological and pathological conditions; and synthesis of glycerophosphatides as well as phospho- and glycosphingolipids. This book is a valuable source of information for biochemists and medical research workers as well as virologists, microbiologists, plant physiologists, and agronomists.