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This book is a collection of selected and relevant research, concerning the developments within the Cell Death field of study. Each contribution comes as a separate chapter complete in itself but directly related to the books topics and objectives. The target audience comprises scholars and specialists in the field.
This book is devoted to botany and covers topical issues in this diverse area of study. The contributions are designed for researchers, graduate students and professionals. The book also presents reviews of current issues in plant-environment interactions making it useful to environmental scientists as well. The book is organized in three sections. The first section includes contributions on responses to flood stress, tolerance to drought and desiccation, phytotoxicity to Chromium and Lead; the second has aspects of economic botany including a review of Smut disease in sugarcane and properties of plant extract used Tassaboount date juice; the last covers topical issues on morphogenesis and genetics on cotton fiber special cell, secretory glands Asphodelus aestivus flower ,pollen tube growth in Leucojum aestivum , morphological studies of Ardisia crenata complex, and hybrid lethality in the Genus Nicotiana.
This book examines the crucial role of a unique alpha-fetoprotein (AFP) in the treatment of cancer. AFP can deliver toxins through specific receptors re-expressed in the majority of cancer cells, serving as a targeted chemotherapy. More importantly, AFP+toxin harnesses the patient’s immune system in order to attack cancer. Depleting the regulatory top monocyte-derived suppressor cells (MDSCs) activates both the innate and adaptive immune responses. The thoroughly chosen toxins switch on apoptosis in MDSCs, restore the broken one in cancer cells, and destroy them naturally without any harmful by-products. Injections with AFP+toxin preparations have shown promising results in animals and the treatment of cancer patients. In addition to this breakthrough, the book also discusses the peroral administration of porcine AFP non-covalent complexes with selected toxins in patients with metastases. It will appeal to science researchers, clinicians, and medical students, as well as the more general reader.
This book covers the basic concepts of phytodermatoses and groups of compounds in plants that have such physiological effects on humans. In order to allow the reader a better understanding of phytodermatoses, skin reactions caused by contact with plants are classified as allergic contact dermatitis, irritant contact dermatitis, contact urticarial, and phytophoto dermatitis. Dermatoses are caused by certain plant constituents that are often classified into groups, such as alkaloids, glycosides, glucosinolates, saponins, phenols, and other compounds. The book also describes 68 plants species that cause dermatoses in humans, especially in those who are engaged in their production, cultivation, planting, pruning, arranging and selling. The plants are classified into 25 families to which they belong. For each plant, the morphological description, habitat, distribution, variability, and their main constituents with toxic and dermatological effects are given.
Rainwater Catchment Systems for Domestic Supply provides a state-of-the-art review of practice in the collection of rainwater. It presents case studies with numerous examples from around the world which will help anyone intending to design or construct a rainwater catchment system. The prime focus of the book is on implementation of roof and ground catchment systems for meeting either total or supplementary household water requirements. All aspects of design and construction are covered including simple methods of sizing systems, erection of gutters, choice of materials, construction techniques, training, operation and maintenance. In addition, non-technical factors such as water quality, he...
Starting with discussion of basic concepts and the molecular mechanisms of necrosis, this book looks first at several forms of necrotic cell death that have been identified, including necroptosis, autophagic cell death, and PARP-mediated cell death. As necrotic cell death is increasingly known to play a critical role in many physiological processes, the next chapters discuss its effect on metabolism, inflammation, immunity, and development. Necrotic cell death is closely implicated in human diseases like cancer, so the next chapters examine its relevance to human diseases, and final chapters cover methodologies for measuring necrosis. This book presents comprehensive coverage of necrosis from recognized experts from leading academic and medical institutions around the world. In contrast to apoptosis, well-defined as a form of programmed cell death, necrosis used to be considered as accidental (i.e., non-programmed) cell death, usually in response to a severe injury. Accumulating evidence now suggests, however, that necrosis is also programmed and controlled by distinctive "death machinery" in response to various stimuli like oxidative stress or DNA damage.
Translated from the German by Maquet, P.; Furlong, R.
The optimal management of breast cancer patients relies on the expertise of a team of medical specialists including radiologists, surgeons, radiation therapists and medical oncologists. Much of the progress in breast cancer management made over the last several years reflects the translation of observations made in the laboratory to the clinic. Critically evaluating the impact of new treatment approaches relies on a commitment to well-designed clinical trials. In this volume, Advances in Breast Cancer Management, a renowned group of breast cancer experts have been asked to provide their perspective on management issues that directly effect patients on a day-to-day basis. Dr. Melody Cobleigh ...
For the first time, the 92-metre frieze of the Voortrekker Monument in Pretoria, one of the largest historical narratives in marble, has been made the subject of a book. The pictorial narrative of the Boer pioneers who conquered South Africa’s interior during the 'Great Trek' (1835-52) represents a crucial period of South Africa’s past. Conceptualising the frieze both reflected on and contributed to the country’s socio-political debates in the 1930s and 1940s when it was made. The book considers the active role the Monument played in the rise of Afrikaner nationalism and the development of apartheid, as well as its place in post-apartheid heritage. The frieze is unique in that it provi...