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Color Atlas of Dermatoimmuno Histocytology
More than 25 years have elapsed since the first application of immunofluorescent techniques in dermatology. These techniques have shed light on many problems concerning skin disorders. Microorganisms, antigens and antibodies, complements and enzymes have been observed in both intracellular and extracellular tissues. This is the first comprehensive atlas on dermato-immuno-histocytology; it collects the most outstanding studies and accompanying photographs carried out by 83 Japanese dermatologists.
Current Catalog
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Immunofluorescence in Clinical Immunology
Immunofluorescence, a suitable laboratory method for the microscopic demonstration of antigens and antibodies in biological materials, useable, for example, to provide evidence for the pathogenesis of disease in histological or cytological preparations and for tumour cell differentiation. For this reason immunofluorescence has a decisive role as the method of choice for the diagnosis of auto-immune diseases. This primer on immunofluorescence techniques, which first appeared in 1979, is a richly illustrated handbook suitable for everyday practical work in the laboratory, useable as both an introduction to the subject as well as an atlas. In hardly any other area of medicine are there so many new findings to report. The second edition of this book is concerned not only with the detection methods which now form an essential and established part of diagnostic techniques, but also with the most recent research results such as the discovery of antibodies against Auerbach's plexus and against podocytes...
Immunization
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Behçet's Disease
This book, besides reviewing basic and clinical aspects of Behçet's disease, covers the latest findings, including genetic studies and treatment with biologics for the disease. Although the cause of Behçet's disease is still unknown, it is well known that genetic factors, such as HLA-B51, are involved in its development. Recently, novel susceptibility loci including IL10, IL23R-IL12RB2, and endoplasmic reticulum aminopeptidase 1 have been identified, providing new insights into the pathogenesis of the disease. In addition to basic research, the beneficial efficacy of anti-TNF-alpha monoclonal antibodies has also been suggested for not only uveitis associated with the disease but also other subtypes of the disease such as entero-, vasculo-, and neuro- Behçet's disease. Behçet's Disease: From Genetics to Therapies provides essential information both for basic researchers working in the fields of immunology, inflammation, and genetics, and for clinical physicians who are interested in Behçet's disease, such as ophthalmologists, rheumatologists, dermatologists, gastroenterologists, neurologists, and vascular surgeons.
Approach and Observation in Clinical Dermatology
SECTION 1: Approach in Dermatology Part 1: General 1. Fever with Rash in an Adult Patient 2. A Patient with Purpura 3. A Patient with Target or Targetoid Lesions 4. A Patient with Suspected Cutaneous Adverse Drug Reaction: Practice Tips 5. A Patient with Generalized Pruritus without Skin Lesions 6. A Patient with Annular Skin Lesions 7. A Suspected Case of Panniculitis 8. A Patient of Facial Melanosis Part 1: A Patient of Facial Hypermelanosis Part 2: A Patient with Facial Hypomelanosis Part 2: Disorders of Nail and Hair 9. Trachyonychia 10. A Case of Hirsutism 11. A Patient with Diffuse Hair Loss 12. A Patient with Cicatricial Alopecia 13. A Patient with Premature Graying of Hair Part 3: In...
Dermal and Ocular Toxicology
Dermal and Ocular Toxicology: Fundamentals and Methods is a procedurally-oriented volume of detailed methods and practical examples discussing the dermal and ocular aspects of toxicology. The book is divided into a dermal section and an ocular section. Each section begins with a chapter on the anatomy and physiology of each organ system and then progresses to more specialized chapters discussing such topics as the toxicological pathology of each system, state-of-the-art in vitro and in vivo evaluatory procedures, statistical considerations for test design and data interpretation, and the utilization of test findings. Test methods are provided for acute dermal exposure effects, dermal hypersensitivity and photoallergy assessment, dermal and ocular 0.pharmacokinetics, skin flap and skin grafting techniques, and in vitro alternative methods. This book can be used as an instructional text or as a sourcebook for practicing toxicologists, pharmacologists, industrial hygienists, occupational health professionals, and graduate students.
