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A core institution in the human endeavor—the public research university—is in transition. As U.S. public universities adapt to a multi-decadal decline in public funding, they risk losing their essential character as a generator, evaluator, and archivist of ideas and as a wellspring of tomorrow’s intellectual, economic, and political leaders. This book explores the core interdependent and coevolving structures of the research university: its physical domain (buildings, libraries, classrooms), administration (governance and funding), and intellectual structures (curricula and degree programs). It searches the U.S. history of the public research university to identify its essential qualities, and generates recommendations that identify the crucial roles of university administration, state government and federal government.
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Tobacco use is the leading cause of preventable death in United States, causing more than 440,000 deaths annually and resulting in $193 billion in health-related economic losses each year-$96 billion in direct medical costs and $97 billion in lost productivity. Since the first U.S. Surgeon General's report on smoking in 1964, more than 29 Surgeon General's reports, drawing on data from thousands of studies, have documented the overwhelming and conclusive biologic, epidemiologic, behavioral, and pharmacologic evidence that tobacco use is deadly. This evidence base links tobacco use to the development of multiple types of cancer and other life-threatening conditions, including cardiovascular a...
Charting the dramatic and complex history of tobacco politics in California between 1975 and 2000, this text provides a graphic demonstration of the successes and failures of both the tobacco industry and public health forces.
Since biological tissues are unstable in an oxygen atmosphere, a great deal of effort is expended by organisms to metabolically limit or repair oxidative tissue damage. This volume of Methods in Enzymology and its companion Volume 234 present methods developed to investigate the roles of oxygen radicals and antioxidants in disease. Key Features* Generation, detection, and characterization of oxygen radicals, chemistry, biochemistry, and intermediate states of reductio* Isolation, characterization, and assay of enzymes or substrates involved in formation or removal of oxygen radical* Methods for assessing molecular, cell, and tissue damage; assays and repair of oxidative damage.
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