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The field of DNA vaccines has undergone explosive growth in the last few years. As usual, some historical precursors of this approach can be d- cerned in the scientific literature of the last decades. However, the present state of affairs appears to date from observations made discreetly in 1988 by Wolff, Malone, Felgner, and colleagues, which were described in a 1989 patent and published in 1990. Quite surprisingly, they showed that genes carried by pure plasmid DNA and injected in a saline solution, hence the epithet “naked DNA,” could be taken up and expressed by skeletal muscle cells with a low but reproducible frequency. Such a simple methodology was sure to spawn many applications....
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Newton genealogy, genealogical, biographical, historical being a record of the descendants of Richard Newton of Sudbury and Marlborough, Massachusetts 1638, with genealogies of families descended from the immigrants, Rev. Roger Newton of Milford, Connecticut; Thomas Newton of Fairfield, Connecticut; Matthew Newton of Stonington, Connecticut; Newtons of Virginia; Newtons near Boston.
In recent years there has been a growing body of evidence from fields such as public health, architecture, ecology, landscape, forestry, psychology, sport science, psychiatry, geography suggesting that nature enhances psychological health and wellbeing. Physical activity in the presence of nature, feelings of connection to nature, engagement with nature, specific environmental features (e.g. therapeutic, water and trees) and images of real and virtual nature have all been posited as important wellbeing facilitators. Thus, the association between natural environments and health outcomes might be more complex than initially understood (Pritchard, Richardson, Sheffield, & Mcewan, 2019). Despite...
Snakes of the World: A Catalogue of Living and Extinct Species, published in 2014, was the first catalogue of its kind and covered all living and fossil snakes described between 1758 and 2012. This new volume will be a supplement to this important herpetological reference and will include new published data on snakes named and recognized since 2012. Key Features Supplements and updates Wallach et al. – Snakes of the World – the only work to cover all living snakes in the world. Includes updates for fossil snakes named since the publication of Wallach et al. Summarizes the systematic snake literature published since the appearance of Wallach et al. Genera and species are listed alphabetically for ease of reference. Related Titles Wallach, V., K. L. Williams, and J. Boundy. Snakes of the World: A Catalogue of Living and Extinct Species (ISBN 978-1-138-03400-6) Aldridge, R. D. and D. M. Sever, eds. Reproductive Biology and Phylogeny of Snakes (ISBN 978-1-57808-701-3) Caldwell, M. W. The Origin of Snakes: Morphology and the Fossil Record (ISBN 978-1-4822-5134-0)