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Handbook of ATPases
ATP-dependent active ion transport enables cells to regulate their pH value and to control their ion composition. The reverse process, transforming an ion imbalance into chemical energy, drives mitochondrial and chloroplast ATP synthesis. The mediators of these fundamental processes are ion-motive ATPases, highly conserved enzymes that play key roles in cell physiology from bacteria to man. As the first comprehensive overview of this important class of enzymes, this handbook summarizes recent knowledge about the molecular mechanism of ATPases, relating this information to the physiology and pathopyhsiology of ion transport, mitochondrial function, vesicle transport and lysosomal acidification. All important P-type, F-type and V-type ATPases are treated systematically, complemented by a special section on the cell biology and physiology of acidic compartments, and backed by an extensive bibliography and index. This premier reference source for physiologists, molecular biologists, biophysicists and clinical researchers contains contributions by the world's foremost ATPase research groups.
Drug Discovery for Psychiatric Disorders
This is a wide scope and in-depth coverage of the state of the art and future directions in drug discovery for major psychiatric disorders.
Cardiovascular Physiology in the Genetically Engineered Mouse
The enormous advances in molecular biology and genetics coupled with the progress in instrumentation and surgical techniques have produced a voluminous and often bewildering quantity of data. The need for a second edition of Cardiovascular Physiology in the Genetically Engineered Mouse is underscored not only by these rapid advances, but by the increasing numbers of scientists who have focussed their research on genetically engineered mice. It is the primary objective of this second edition to interpret critically the literature and to provide a framework for the enormous amount of information in this burgeoning field. As in the first edition, the monograph serves as a practical guide for th...
Molecular Mechanisms of Cardiac Hypertrophy and Failure
This title reviews current knowledge of the mechanisms contributing to heart failure. Editor Richard Walsh and an internationally renowned team of contributors discuss key advances in molecular and cell biology, biochemistry, and pharmacology, focusing on advances that have a direct bearing on current clinical studies. It highlights developments across a broad range of disciplines, with in-depth coverage of each topic providing background and perspective on current literature. By setting new advances in a broader context, this text allows readers to compare different ideas and evaluate their importance in their own areas of research or clinical practice.
Principles of Turbomachinery
The text is based on a course on turbomachinery which the author has taught since year 2000 as a technical elective. Topics include; Energy Transfer in Turbomachines, Gas and Steam Turbines, and Hydraulic Turbines. New material on wind turbines, and three-dimensional effects in axial turbomachines is included. The level is kept as such that students can smoothly move from a study of the most successful books in thermodynamics, fluid dynamics, and heat transfer to the subject of turbomachinery. The chapters are organized in such a way that the more difficult material is left to the later sections of each chapter. Thus, depending on the level of the students, instructors can tailor their cours...
Handbook of Turbomachinery
Building on the success of its predecessor, Handbook of Turbomachinery, Second Edition presents new material on advances in fluid mechanics of turbomachinery, high-speed, rotating, and transient experiments, cooling challenges for constantly increasing gas temperatures, advanced experimental heat transfer and cooling effectiveness techniques, and propagation of wake and pressure disturbances. Completely revised and updated, it offers updated chapters on compressor design, rotor dynamics, and hydraulic turbines and features six new chapters on topics such as aerodynamic instability, flutter prediction, blade modeling in steam turbines, multidisciplinary design optimization.
NBS Technical Note
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Mysore Law Reports
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