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Dieses Fachbuch legt den Schwerpunkt auf konkrete Methoden und die jüngsten Fortschritte bei der Anwendung von Nanotechnologie für die Entwicklung neuer medikamentöser Therapieansätze und die medizinische Diagnostik. Von den Grundlagen der Nanopharmazie, einschließlich Charakterisierung und Herstellungsverfahren, bis hin zur Rolle von Nanopartikeln und Wirkstoffen wird das Fachgebiet umfassend dargestellt. Anwendungsbeispiele beziehen sich auf Fragestellungen bei der Medikamentenentwicklung und die Übertragung auf die klinische Praxis, Marktchancen und Aspekte der industriellen Vermarktung. Die beschriebenen Anwendungen stammen aus der Behandlung von Krebserkrankungen und weiteren wichtigen Therapiebereichen wie Infektionskrankheiten und Dermatologie. Abgerundet wird das Fachbuch durch eine ausführliche Erörterung sicherheitsrelevanter, rechtlicher und gesellschaftlicher Fragen. Geschrieben von einem erstklassigen Team von Herausgebern und Autoren, die zu den führenden Experten in Europa und den USA sowie zu den Pionieren der Nanopharmazie gehören.
New Insights into Glioblastoma: Diagnosis, Therapeutics and Theranostics provides a compendium of recent diagnostic and therapeutic advances in GBM, encompassing a pipeline of compounds and (bio) nanotechnology strategies that have stood out with potential increased antitumoral activity and capability to cross the blood-brain barrier. Issues and challenges related to their translation into the clinical practice and their contribution to the increase in survival rates and well-being of patients are addressed. This is a valuable resource for graduate students, oncologists, cancer researchers and members of the biomedical field who need to learn more on recent developments on the management of ...
While advances in both the treatment of cancer and the management of its complications have led to significant improvement in patient survival, infections remain a significant cause of morbidity and mortality in patients with neo plastic disease. In this patient population, infection risk results from a complex interplay between the host’s underlying immunodeficiencies, local tumor effects and treatment-induced immunosuppression. New chemotherapeutic approaches and antimicrobial prophylaxis and treatment practices continue to shape the spectrum of infections in these patients. Clinicians who treat infections in cancer patients are continually challenged by the emergence of new pathogens an...
The Duke and the Stars explores science and medicine as studied and practiced in fifteenth-century Italy, including how astrology was taught in relation to astronomy. It illustrates how the “predictive art” of astrology was often a critical, secretive source of information for Italian Renaissance rulers, particularly in times of crisis.
This book presents the results of a unique macroscopic and radiological analysis, by X-ray and CT scan, of the bone pathologies of about 1800 subjects who lived at the time of the Roman Empire (first and second centuries A.D.) and whose remains were recovered during the excavation of a suburban necropolis of Rome. The survey, which represents a collaboration between the Italian Society of Orthopaedics and Traumatology and the Special Superintendent for the Archaeological Heritage of Rome, has yielded incredible images of different orthopaedic diseases in a period when no surgical treatment was available: there are cases of infection (osteomyelitis), metabolic disease (gout), hematologic dise...
Print Culture Through the Ages: Essays on Latin American Book History, is a compendium of specialized essays by renowned scholars from Mexico, the United States, Argentina, Uruguay, France, and Colombia that focuses on various topics involving the evolution of printing, reading publics, the publishing process and literary development during periods of political and cultural change in Latin America. The volume has four primary areas of concern, namely “Labors of the Printing Press, Typography and Editing”; “Books and Readers in the Colonial Period”; “New Forms of Literary Consumption”; “The Press and Its Readers”. It will be of particular interest to scholars in the areas of literature, book history, print culture and images.