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Over the last years, thanks to growing advances in the field of cancer therapies, a considerable decrease in cancer mortality has been observed. Unfortunately, such therapies have shown a wide spectrum of cardiotoxicities. This book provides the readers with the latest advances and insights in the ever-expanding field of Cardio-Oncology. Specific topics discussed in the book include the potential role of inflammation in Cardio-Oncology and the description of the different manifestations of cardiotoxicities (including vascular toxicity, systemic hypertension, arrhythmias), analyzing the complex relationships between cancer and heart failure, two conditions whose prevalence increases with ageing. Furthermore, the role of biomarkers and imaging in cardio-oncology is discussed.
This proposed text is designed to provide a useful and comprehensive resource and state-of-the-art overview to readers about vascular damage potentially induced by antineoplastic drugs. Thanks to more and more effective antineoplastic treatments the survival of cancer patients is enormously increasing, but at the same time it is increasing the burden of related cardiovascular complications that affect morbidity and mortality. On this basis a new branch of cardiology has been developed, that is Cardio-Oncology. The aim is to prevent cardiovascular complications related to cancer therapy and to facilitate and avoid interruption of antineoplastic drugs due to the occurrence of cardiovascular da...
The role of ROS/RNS signaling in cardiovascular functions and diseases is increasingly emerging in the last decades. The involvement of ROS/RNS in the control of a large number of cardiovascular functions like the regulation of the vascular tone, the control of blood pressure or myocyte excitation-contraction coupling and force development has been broadly investigated and in part clarified. On the other hand, many efforts have been focused in clarifying the redox mechanisms involved in cardiovascular diseases like ischemia/reperfusion injury, diabetes-associated cardiovascular dysfunctions, atherosclerosis or hypertension, just to mention the major ones. However, in most cases the two level...
In this issue of Heart Failure Clinics, guest editors Drs. Alberto M. Marra, Pietro Ameri, and Alexander E. Sherman bring their considerable expertise to Challenges in Pulmonary Hypertension. Top experts in the field cover key topics such as gender aspects in pulmonary hypertension; PAH in connective tissue diseases beyond systemic sclerosis; genetic background of high altitude pulmonary edema; oxygen therapy in pulmonary vascular disease; and more. - Contains 13 relevant, practice-oriented topics including rare forms of pulmonary hypertension; management of SARS-CoV-2 infection and COVID-19 in patients with pulmonary arterial hypertension; anabolic deficiency in pulmonary arterial hypertension; anticoagulation in pulmonary hypertension; and more. - Provides in-depth clinical reviews on challenges in pulmonary hypertension, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
The American Heart Association’s Scientific Sessions 2019 is bringing big science, big technology, and big networking opportunities to Philadelphia, Pennsylvania this November. This event features five days of the best in science and cardiovascular clinical practice covering all aspects of basic, clinical, population and translational content.
Advances in Hyperinsulinism Research and Treatment: 2013 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about ZZZAdditional Research in a concise format. The editors have built Advances in Hyperinsulinism Research and Treatment: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about ZZZAdditional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Hyperinsulinism Research and Treatment: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Nessuno pensa che possa tornare il fascismo storico, il regime dittatoriale dell'olio di ricino e del manganello, delle camicie nere e del fez. Ma il successo elettorale e l'arrivo al governo degli eredi diretti di un partito fondato dai reduci del Partito nazionale fascista e della Repubblica sociale italiana ha spalancato scenari imprevedibili fino a poco tempo fa e tuttora impensabili in gran parte d'Europa. Nell'Italia del 2024, in parlamento, al governo, ai vertici di istituzioni statali ci sono persone che celebrano le ricorrenze e le personalità del Ventennio, manifestano apertamente la loro allergia a tutto ciò che sa di antifascismo, assorbono e diffondono l'antisemitismo e il raz...
Francesco, appena uscito dalla Accademia Militare di Modena con una laurea in Ingegneria e una seconda in Legge, si arruola in Polizia e viene nominato Vice Questore Aggiunto, proprio presso la Questura della sua città natale, Brescia. Come primo importante incarico gli viene assegnato il compito di indagare sulla morte di una ragazza ucraina, ferocemente torturata e strangolata. Attraverso minuziose indagini, arresta una organizzazione con a capo un magnate russo che con vari stratagemmi importava oro dalla Cina per acquistare armi per la madrepatria in guerra con l’Ucraina. Da qui riesce a scoprire i legami con la mafia nigeriana che gestiva lo spaccio di droga e la tratta di schiave pe...