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Pulmonary Fibrosis
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Immune-Mediated Lung Injury
A possible association between interstitial lung diseases and autoimmunity was first reported almost 40 years ago. Despite further reports linking immune deregulation and chronic lung injury, the role of autoimmunity had been severely underscored in the past mainly due to the disappointing results of immunosuppressive and immunomodulatory agents such as corticosteroids in patients with idiopathic pulmonary fibrosis. Most recently, the interest has been revived. Clinical observations fueled mechanistic discoveries on the role of immunity in lung injury and the identification of autoimmune phenomena as part of the fibrotic process. With this Research Topic, we, therefore, aim to improve knowledge for the association of immunity and interstitial lung diseases.
Governing Medical Knowledge Commons
This book collects fifteen new case studies documenting successful knowledge and information sharing commons institutions for medical and health sciences innovation. Also available as Open Access.
Mechanisms of Neuronal Migration during Corticogenesis
The cerebral cortex plays central roles in many higher-order functions such as cognition, language, consciousness, and the control of voluntary behavior. These processes are performed by the densely interconnected networks of excitatory pyramidal neurons and inhibitory interneurons, and the balanced development of these two types of neuron is quite important. During cortical development, pyramidal neurons and interneurons show quite different migratory behaviors: radial migration and tangential migration, respectively. Pyramidal neurons are generated in the ventricular zone of the dorsal telencephalon, and migrate radially along radial glial fibers toward the pial surface, forming a six-laye...
Genome Research
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Bioinformatics and Beyond
This book is a comprehensive exploration of the dynamic interplay between bioinformatics and artificial intelligence (AI) within the healthcare landscape. This book introduces readers to the foundational principles of bioinformatics and AI, elucidating their integration and collaborative potential. Bioinformatics and Beyond: AI Applications in Healthcare explores the transformative impact of data-driven insights, showcasing the applications of machine learning in diagnostics, personalized medicine, and genomic advancements. The book unveils the pivotal role AI plays in accelerating pharmaceutical research. Moreover, it addresses the practical implementation of AI in clinical decision support...
Science
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