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Practical Handbook of Neurosurgery
“Practical Handbook of Neurosurgery” invites readers to take part in a journey through the vast field of neurosurgery, in the company of internationally renowned experts. At a time when the discipline is experiencing a (detrimental) tendency to segment into various subfields and scatter in the process, it can be worthwhile to collect a number of practical lessons gleaned from experienced and leading neurosurgeons. The book also aims to present numerous important figures in the neurosurgical community, with a brief overview of the vitae and main contributions for each. We must confess that we were sad that some of the most active members were unable to participate, likely due to time cons...
Single Cell Transcriptomics
This volume provides up-to-date methods on single cell wet and bioinformatics protocols based on the researcher experiment requirements. Chapters detail basic analytical procedures, single-cell data QC, dimensionality reduction, clustering, cluster-specific features selection, RNA velocity, multi-modal data integration, and single cell RNA editing. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Single Cell Transcriptomics: Methods and Protocols aims to be a valuable resource for all researchers interested in learning more about this important and developing field.
Neurosurgery
In a specialized field such as neurosurgery, highly specific knowledge is required. Training programs in the EU vary, making it difficult to standardize medical training. This manual forms the basis for a European consensus in neurosurgery. It is written for residents, students and physicians with a special interest in neurosurgery. Diagnostic and therapeutic procedures are detailed according to localization (cranial, spinal, peripheral nerves) with special consideration given to congenital defects and pediatric neurosurgical disorders, functional and stereotactic neurosurgery, as well as critical neurosurgical care. Each chapter contains the basics of anatomy and physiology. The book is well-organized and clearly structured according to each entity and its neurosurgical treatment options. A better understanding of specific neurosurgical problems will help practicing neurosurgeons provide better medical care for their patients, and will also provide the neurosurgery resident with a reliable European standard for step-by-step management of neurosurgical problems, which will prove useful when preparing for the board examination.
Advances and Technical Standards in Neurosurgery
Advances: H. Duffau: Subpial dissection and subcortical mapping with vasculature and white matter pathways preservation in surgery for brain (low grade) gliomas. - F. Scholtes, G. Brook, D. Martin: Spinal cord injury and its treatment: current management and experimental perspectives. - M. Sindou, M. Messerer, J. Alvernia, G. Saint-Pierre: Percutaneous Biopsy through the Foramen Ovale for Parasellar lesions: Surgical anatomy, Method and Indications. - Technical Standards: C. Raftopoulos, F. Waterkeyn, E. Fomekong, T. Duprez: Percutaneous pedicle screw implantation with robotic intraoperative 2D/3D fluoroscopy for refractory low back pain. – I. Zemmoura, S. Velut, P. Francois:The choroidal fissure: anatomy and surgical implications. – I. Timofeev, T. Santarius, A.G. Kolias, P.J.A. Hutchinson: Decompressive craniectomy – operative technique and perioperative care. - S Fauser, J Zentner: Management of complex cortical dysplasia in epilepsy
Regulation of Gene Expression by Small RNAs
New Findings Revolutionize Concepts of Gene FunctionEndogenous small RNAs have been found in various organisms, including humans, mice, flies, worms, fungi, and bacteria. Furthermore, it's been shown that microRNAs acting as cellular rheostats have the ability to modulate gene expression. In higher eukaryotes, microRNAs may regulate as much as 50 p
Genomics Research on Non-Model Plant Pathogens: Delivering Novel Insights into Rust Fungus Biology
Fungi of the order Pucciniales cause rust diseases on many plants including important crops and trees widely used in Agriculture, forestry and bioenergy programs; these encompass gymnosperms and angiosperms, monocots and dicots, perennial and annual plant species. These fungi are obligate biotrophs and -except for a few cases- cannot be cultivated outside their hosts in a laboratory. For this reason, standard functional and molecular genetic approaches to study these pathogens are very challenging and the means to study their biology, i.e. how they infect, develop and reproduce on plant hosts, are rather limited, even though they rank among the most devastating pathogens. Among fungal plant ...
PCR Technology
PCR's simplicity as a molecular technique is, in some ways, responsible for the huge amount of innovation that surrounds it, as researchers continually think of new ways to tweak, adapt, and re-formulate concepts and applications. PCR Technology: Current Innovations, Third Edition is a collection of novel methods, insights, and points of view that
The PCR Revolution
Examines the latest innovations and the overall impact of PCR on areas of molecular research.
Pineal Region Lesions
Neurosurgical lesions of the pineal region are extremely rare, accounting for roughly 1% of the total number of neurosurgical expansive lesions in modern practice. This book offers an up-to-date review of the relevant literature, combined with the personal perspectives of some highly experienced figures in the field. The book is divided into two main parts, the first of which offers an overview of the pineal region from an anatomic, pathologic, imaging and therapeutic perspective. Special attention is given to surgical approaches to pineal region lesions. Microsurgical techniques are presented, together with detailed indications regarding specific locations of these lesions, specific complic...
