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Hepatitis B (HBV) infection is a major public health problem and cause of chronic liver disease. The 2024 HBV guidelines provide updated evidence-informed recommendations on key priority topics. These include expanded and simplified treatment criteria for adults but now also for adolescents; expanded eligibility for antiviral prophylaxis for pregnant women to prevent mother-to-child transmission of HBV; improving HBV diagnostics through use of point-of-care HBV DNA viral load and reflex approaches to HBV DNA testing; who to test and how to test for HDV infection; and approaches to promote delivery of high-quality HBV services, including strategies to promote adherence to long-term antiviral therapy and retention in care. The 2024 guidelines include 11 updated chapters with new recommendations and also update existing chapters without new recommendations, such as those on treatment monitoring and surveillance for liver cancer.
Ranging from the imperial palaces of ancient China and the bakeries of fourteenth-century Genoa and Naples all the way to the restaurant kitchens of today, Pasta tells a story that will forever change the way you look at your next plate of vermicelli. Pasta has become a ubiquitous food, present in regional diets around the world and available in a host of shapes, sizes, textures, and tastes. Yet, although it has become a mass-produced commodity, it remains uniquely adaptable to innumerable recipes and individual creativity. Pasta: The Story of a Universal Food shows that this enormously popular food has resulted from of a lengthy process of cultural construction and widely diverse knowledge,...
Forgiveness, Empathy, Compassion, and Kindness—these four fundamental human values are the key to unlocking great unity and humanity. In It’s Time to Give a FECK, Chaz Ebert takes the reader through a heartfelt journey of how the four FECK Principles have prevailed through the most adverse circumstances and united strangers in the name of love. Read on to discover the stories and science as to how the elevation of our personal humanity is key to keeping humanity as a whole united. None of us has to go it alone. Since her husband’s, Roger Ebert’s, death on April 4, 2013, it has been Chaz Ebert’s fervent desire for things such as forgiveness, empathy, compassion, and kindness—the F...
Worldwide there is a generalized trend toward aged societies. Between 2015 and 2050, the proportion of the world's population over 60 years will nearly double from 12% to 22%. As life expectancy continues to increase and natality rates lower, not only the composition of countries will change, but also its health landscape. However, an increased life expectancy does not necessarily mean a healthy life. In most high-income countries more than 20% of those years are lived in ill health due to chronic conditions caused by non-communicable diseases, which compromises functional ability and well-being - key components of healthy aging. In this way, not only people's lives but also societal structu...
This book provides a comprehensive examination of the pharmaceutical and medical device industry, including analysis of its current trade and innovation strategies. Opening with a survey of the global pharmaceutical and medical device industry, Bhardwaj outlines the growing trade and trade interdependence among countries in the global supply chain. He adopts a trade competitiveness approach to analyze patterns of product specialization and examines the drug discovery process and its challenges in translating bioscientific knowledge into lifesaving products. Bhardwaj argues that further economic integration, collaborative R&D, and digital technologies may help accelerate productivity and addr...
The 2010 International Conference on Life System Modeling and Simulation (LSMS 2010) and the 2010 International Conference on Intelligent Computing for Sustainable Energy and Environment (ICSEE 2010) were formed to bring together researchers and practitioners in the fields of life system modeling/simulation and intelligent computing applied to worldwide sustainable energy and environmental applications. A life system is a broad concept, covering both micro and macro components ra- ing from cells, tissues and organs across to organisms and ecological niches. To c- prehend and predict the complex behavior of even a simple life system can be - tremely difficult using conventional approaches. To...
The Public Engagement and Crowdfunding Practical Guide provides a map for researchers, innovators, community members, and others on how to organize public engagement in preparation for research crowdfunding.