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Genes and Resistance to Disease
The advances in human genetics that have ocurred during the past 20 years have revolutionized our knowledge of the role played by inheritance in health and disase. It is clear that our DNA determines not only the emergence of catastrophic single-gene disorders, which affect millions of persons worldwide, but also interacts with environments to predispose individuals to cancer, allergy, hypertension, heart disease, diabetes, psychiatric disorders and even to some infectious diseases. Overall, the study of longevity and the demonstration of genes favouring a long lifespan suggest that such protective systems exist. In recent years, the study of genetic polymorphisms has made clear that some alleles have beneficial effects. These discoveries can substantially improve our understanding of the interactions between genetics and the environment, between pathogenetic mechanisms and new treatments.
Guide to Cytochromes
Cytochromes are coloured iron-containing proteins that transfer electrons during cellular respiration and photosynthesis. The Cytochrome P450 family of enzymes catalyze reactions whereby water-insoluble drugs or metabolites, that would otherwise reach toxic levels in cell membranes, are rendered suitably water-soluble to leave the cell and be excreted in the urine. Due to the extensive nature of this subject, which is an area of intense scientific interest, the field is rapidly advancing and there is a need for new textbooks to keep abreast of the latest developments. The book fulfils that role in providing a fast-track approach for those coming into the P450 field, either at postgraduate le...
Dracula
A celebration of the Dracula legend - it's origins, incarnations and impact on Western culture. Written by someone considered to be the World's premier Dracula scholar.
Blood Thirst
In Blood Thirst: One Hundred Years of Vampire Fiction, Leonard Wolf gathers thirty tales in which vampires of all varieties make their ghastly presence felt.
Frontiers in Medicinal Chemistry
""Frontiers in Medicinal Chemistry" is an Ebook series devoted to the review of areas of important topical interest to medicinal chemists and others in allied disciplines. "Frontiers in Medicinal Chemistry" covers all the areas of medicinal chemistry, incl"
Brute Force
Considers how dangerous beasts in horror films illuminate the human-animal relationship. It’s always been a wild world, with humans telling stories of killer animals as soon as they could tell stories at all. Movies are an especially popular vehicle for our fascination with fierce creatures. In Brute Force, Dominic Lennard takes a close look at a range of cinematic animal attackers, including killer gorillas, sharks, snakes, bears, wolves, spiders, and even a few dinosaurs. Lennard argues that animal horror is not so much a focused genre as it is an impulse, tapping into age-old fears of becoming prey. At the same time, these films expose conflicts and uncertainties in our current relation...
Soft Computing Approaches in Chemistry
The contributions to this book cover a wide range of applications of Soft Computing to the chemical domain. The early roots of Soft Computing can be traced back to Lotfi Zadeh's work on soft data analysis [1] published in 1981. 'Soft Computing' itself became fully established about 10 years later, when the Berkeley Initiative in Soft Computing (SISC), an industrial liaison program, was put in place at the University of California - Berkeley. Soft Computing applications are characterized by their ability to: • approximate many different kinds of real-world systems; • tolerate imprecision, partial truth, and uncertainty; and • learn from their environment. Such characteristics commonly l...
Melodies of the Mind
In this book, Nagel invites us to take a journey on an aural and oral road that explores music and emotion, and their links to the unconscious.
