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Genes and Resistance to Disease
The advances in human genetics that have ocurred during the past 20 years have revolutionized our knowledge of the role played by inheritance in health and disase. It is clear that our DNA determines not only the emergence of catastrophic single-gene disorders, which affect millions of persons worldwide, but also interacts with environments to predispose individuals to cancer, allergy, hypertension, heart disease, diabetes, psychiatric disorders and even to some infectious diseases. Overall, the study of longevity and the demonstration of genes favouring a long lifespan suggest that such protective systems exist. In recent years, the study of genetic polymorphisms has made clear that some alleles have beneficial effects. These discoveries can substantially improve our understanding of the interactions between genetics and the environment, between pathogenetic mechanisms and new treatments.
Guide to Cytochromes
Cytochromes are coloured iron-containing proteins that transfer electrons during cellular respiration and photosynthesis. The Cytochrome P450 family of enzymes catalyze reactions whereby water-insoluble drugs or metabolites, that would otherwise reach toxic levels in cell membranes, are rendered suitably water-soluble to leave the cell and be excreted in the urine. Due to the extensive nature of this subject, which is an area of intense scientific interest, the field is rapidly advancing and there is a need for new textbooks to keep abreast of the latest developments. The book fulfils that role in providing a fast-track approach for those coming into the P450 field, either at postgraduate le...
Frontiers in Medicinal Chemistry
""Frontiers in Medicinal Chemistry" is an Ebook series devoted to the review of areas of important topical interest to medicinal chemists and others in allied disciplines. "Frontiers in Medicinal Chemistry" covers all the areas of medicinal chemistry, incl"
Dracula
A celebration of the Dracula legend - it's origins, incarnations and impact on Western culture. Written by someone considered to be the World's premier Dracula scholar.
Soft Computing Approaches in Chemistry
The contributions to this book cover a wide range of applications of Soft Computing to the chemical domain. The early roots of Soft Computing can be traced back to Lotfi Zadeh's work on soft data analysis [1] published in 1981. 'Soft Computing' itself became fully established about 10 years later, when the Berkeley Initiative in Soft Computing (SISC), an industrial liaison program, was put in place at the University of California - Berkeley. Soft Computing applications are characterized by their ability to: • approximate many different kinds of real-world systems; • tolerate imprecision, partial truth, and uncertainty; and • learn from their environment. Such characteristics commonly l...
List of Officers of the Department of State, Including the List of Ministers, Consuls, and Other Diplomatic and Commercial Agents of the United States in Foreign Countries
List for March 7, 1844, is the list for September 10, 1842, amended in manuscript.
Howl of the Gods
The city of Moon Valley is being stalked by a savage killer that can move without sound, strike without warning, and whose howl contains a power granted only by the gods themselves. Lieutenant Hal Dillon is drawn into the killer’s grisly web, and as he uncovers the incredible mystery of the killer’s existence, he discovers something even more harrowing. He and the killer are united in a struggle against an enemy that has been stalking both of them for years. Hal finds himself locked in an epic battle between the forces of chaos and death, where the only way for him to win may be to disavow his own humanity. Hal and a group of his friends now must face their ultimate fears, with the fate of humanity hanging in the balance…
General Register
Announcements for the following year included in some vols.
Catalog of Copyright Entries. Third Series
Includes Part 1, Number 2: Books and Pamphlets, Including Serials and Contributions to Periodicals July - December)
