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"The Open Access version of this book, available at https: //doi.org/10.4324/9780429458781, has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 4.0 license." This book examines the uncertainties underlying various strategies for a low-carbon future. Most prominently, such strategies relate to transitions in the energy sector, on both the supply and the demand side. At the same time they interact with other sectors, such as industrial production, transport, and building, and ultimately require new behaviour patterns at household and individual levels. Currently, much research is available on the effectiveness of these strategies but, in order to successf...
O presente texto, desenvolvido a partir duma perspectiva vulgarizadora por dous autores afastados do território da filologia
Presents a novel, evidence-based psychological intervention to help therapists manage cognitive and functional deficits in bipolar disorder patients.
HiC-Pro is an optimized and flexible pipeline for processing Hi-C data from raw reads to normalized contact maps. HiC-Pro maps reads, detects valid ligation products, performs quality controls and generates intra- and inter-chromosomal contact maps. It includes a fast implementation of the iterative correction method and is based on a memory-efficient data format for Hi-C contact maps. In addition, HiC-Pro can use phased genotype data to build allele-specific contact maps. We applied HiC-Pro to different Hi-C datasets, demonstrating its ability to easily process large data in a reasonable time. Source code and documentation are available at http://github.com/nservant/HiC-Pro.
In contrast to existing books on immunoinformatics, this volume presents a cross-section of immunoinformatics research. The contributions highlight the interdisciplinary nature of the field and how collaborative efforts among bioinformaticians and bench scientists result in innovative strategies for understanding the immune system. Immunoinformatics is ideal for scientists and students in immunology, bioinformatics, microbiology, and many other disciplines.
Systems and Synthetic Immunology focuses on the similarities between biology and engineering at the systems level, which are important for applying engineering theories to biology problems. With the advent of new genomic techniques, there are numerous systematic investigations underway in the scientific world. This volume highlights techniques that can be used to effectively combine two of the most essential biological fields - Systems Biology and Synthetic Immunology. The respective chapters discuss the role of synthetic immunology in biotechnology, production of biomaterials, and their use in vaccine delivery. Further topics include the importance of cytokines; the use of genomic engineering tools in immunotherapy; immunosensors; nanotherapeutics; and bioinformatics tools in biomedical applications. Given its scope, the book offers readers an up-to-date and comprehensive review of this unique and dynamic field of research.
The COVID-19 pandemic has disrupted every domain of life. Migration and human mobility in general are not exceptions. Since March 2020, researchers, policy makers and many others have channelled their efforts to understand this new coronavirus, its impact and prospects. Many scholars were thinking and writing on the pandemic from its onset and many blog essays quickly appeared. One of the earliest peer-reviewed research articles Sirkeci and Yucesahin (2020) is reproduced here. This article and its focus on mobility and travel data showed that it was possible to predict the spatial spread and concentration of COVID-19 cases. Not only was this finding crucial to developing appropriate policies...