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Thiamine: Catalytic Mechanisms in Normal and Disease States brings together the most recent developments in thiamine diphosphate (TDP)-requiring enzyme research and details the mechanisms of catalysis and structure-function relationships, as well as pathophysiological aspects of a spectrum of diseases associated with TDP-requiring enzymes. Providing new insights into neurogenerative diseases, this volume associates defects in the function of TDP-dependent enzymes with numerous metabolic disorders and disease states and offers novel aspects of thiamine enzymes in chiral synthesis as well as new perspectives on the cellular role of thiamine triphosphate and thiamine triphosphates.
Progress in Nucleic Acid Research and Molecular Biology provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology. It contains contributions from leaders in their fields and abundant references.
This is a cumulative subject index for volumes 40-72 of Progress in Nucleic Acid Research and Molecular Biology. This series is intended to bring to light the most recent advances in these overlapping disciplines with a timely compilation of reviews comprising each volume. - Cumulative subject index for volumes 40-72 of Progress in Nucleic Acid Research and Molecular Biology. - Brings to light the most recent advances in these overlapping disciplines with a timely compilation of reviews comprising each volume.
American Association for Cancer Research 2019 Proceedings: Abstracts 2749-5314 - Part B
The Spring and Autumn Annals of Master Yan is the biography of the most important statesmen and political thinkers of the Eastern Zhou dynasty China: Yan Ying (d. 500 BCE). Living through an exceptionally troubled period, he served three rulers and two dictators of the state of Qi, in Shandong Province. His experiences informed his revolutionary theories concerning the relationship between the individual and the state. Long considered to be a forgery, recent archaeological discoveries have proved the Spring and Autumn Annals of Master Yan to be a genuinely ancient text. This book provides not only the first complete translation of the text into any Western language, but a detailed analysis of the context in which it was produced.
Precision medicine is an emerging practice by which clinicians aim to deliver a personalized treatment program to affected patients based on information gained from their individual clinical and biological profiles. In the context of precise cancer immunotherapy, multi-omics, high-throughput sequencing, big data, and other approaches serve to screen new predictive factors for immunotherapy response and prognosis in cancer patients.