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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
During the last two decades, our view of the role of reactive oxygen species (ROS) in inflammatory processes has changed dramatically. ROS that are constantly produced at lower levels by living cells metabolizing oxygen contribute to normal cellular function and tissue homeostasis. ROS are produced at higher levels in inflammation and regulate the inflammatory response in specific ways. The role of ROS in inflammation is complex and primarily determined by their relative amount, chemical properties, reactivity, subcellular localization and molecular environment, specificity for their biological targets, and availability and mechanisms of antioxidant defense systems. This eBook comprises twel...