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This thesis describes the use of biophysical and biochemical methods to prove that calcium has a positive feedback effect on amplifying and sustaining CD3 phosphorylation and should enhance T-cell sensitivity to foreign antigens. The study presented shows that calcium can regulate the signal pathway in cells not only as a secondary messenger but also through direct interactions with the phospholipid bilayer. The approach used in the thesis also represents an important advance, as it couples the use of nuclear magnetic resonance (NMR) to the analysis of signaling phenomena in living cells. Moreover, the thesis optimizes the Nanodisc assembly protocol, which can broaden its range of applications in membrane protein studies. A preliminary study on the structure of dengue virus NS2B-NS3p in complex with aprotinin, which may help to develop new drugs against the dengue virus, is also included.
Inspired by the community behaviors of animals and humans, cooperative control has been intensively studied by numerous researchers in recent years. Cooperative control aims to build a network system collectively driven by a global objective function in a distributed or centralized communication network and shows great application potential in a wide domain. From the perspective of cybernetics in network system cooperation, one of the main tasks is to design the formation control scheme for multiple intelligent unmanned systems, facilitating the achievements of hazardous missions – e.g., deep space exploration, cooperative military operation, and collaborative transportation. Various chall...
From A to Z, Abandon Superstitions (1958; Po Chu Mi Xing in Chinese) to Zuo Wenjun and Sima Xiangru (1984; Zuo Wen Jun Ahe Si Ma Xiang Ru), this comprehensive reference work provides filmographic data on 2,444 Chinese features released since the formation of the People's Republic of China. The films reflect the shifting dynamics of the Chinese film industry, from sweeping epics to unabashedly political docudramas, although straight documentaries are excluded from the current work. The entries include the title in English, the Chinese title (in Pinyin romanization with each syllable noted separately for clarity), year of release, studio, technical information (e.g., black and white or color, letterboxed or widescreen), length, technical credits, literary source (when applicable), cast, plot summary, and awards won.
Remote sensing data and techniques have been widely used for disaster monitoring and assessment. In particular, recent advances in sensor technologies and artificial intelligence-based modeling are very promising for disaster monitoring and readying responses aimed at reducing the damage caused by disasters. This book contains eleven scientific papers that have studied novel approaches applied to a range of natural disasters such as forest fire, urban land subsidence, flood, and tropical cyclones.
Selected, peer reviewed papers from the 2014 3rd International Conference on Advanced Engineering Materials and Architecture Science (ICAEMAS 2014), July 26-27, 2014, Huhhot, Inner Mongolia, China
This book includes a selection of reviewed papers presented at the 11th China Academic Conference on Printing and Packaging, held on November 26–29, 2020, Guangzhou, China. The conference is jointly organized by China Academy of Printing Technology and South China University of Technology. With 10 keynote talks and 200 presented papers on graphic communication and packaging technologies, the conference attracted more than 300 scientists. The proceedings cover the recent findings in color science and technology, image processing technology, digital media technology, mechanical and electronic engineering and numerical control, materials and detection, digital process management technology in printing and packaging, and other technologies. As such, the book is of interest to university researchers, R&D engineers and graduate students in the field of graphic arts, packaging, color science, image science, material science, computer science, digital media, network technology and smart manufacturing technology.
This book covers recent advances in artificial intelligence, smart computing, and their applications in augmenting medical and health care systems. It will serve as an ideal reference text for graduate students and academic researchers in diverse engineering fields including electrical, electronics and communication, computer, and biomedical. This book: Presents architecture, characteristics, and applications of artificial intelligence and smart computing in health care systems Highlights privacy issues faced in health care and health informatics using artificial intelligence and smart computing technologies Discusses nature-inspired computing algorithms for the brain-computer interface Cove...
This book – a conjoint effort of ocular oncologists, general oncologists, and pathologists – is a comprehensive source of authoritative information on the subject of ocular and adnexal lymphoma. It covers all aspects, including clinical features, classification, epidemiology, diagnostic evaluation, biopsy techniques, histology and molecular pathology, staging procedures, and treatment methods. Detailed information is provided on primary vitreoretinal and adnexal lymphomas and chapters are also included on rare variants such as T cell lymphoma and reactive lymphoid hyperplasia of the ocular adnexa. The emphasis throughout is on easy readability, and the layout ensures rapid retrieval of information. In order to convey fundamental concepts, numerous tables, clinical photographs, histopathologic microphotographs, and imaging studies (fluorescein and indocyanine angiograms, ultrasonograms, CT scans, and MR images) are included.
This book provides the latest comprehensive methods for isolation and other novel techniques for marine product development. Furthermore, this book offers knowledge on the biological, medical, and industrial applications of marine-derived medicinal food substances. There has been a tremendous increase in the products derived from marine organisms for commercial application in industries every year. Functional foods of medicinal value are particularly in demand as new technology allows the stabilization of natural ingredients and their availability in pure forms to solve various human diseases. Marine flora and fauna have essential elements and trace minerals that nurture various hormones pro...
This book gathers selected papers from the 8th International Field Exploration and Development Conference (IFEDC 2018) and addresses a broad range of topics, including: Reservoir Surveillance and Management, Reservoir Evaluation and Dynamic Description, Reservoir Production Stimulation and EOR, Ultra-Tight Reservoirs, Unconventional Oil and Gas Resources Technology, Oil and Gas Well Production Testing, and Geomechanics. In brief, the papers introduce readers to upstream technologies used in oil & gas development, the main principles of the process, and various related design technologies. The conference not only provided a platform to exchange experiences, but also promoted the advancement of scientific research in oil & gas exploration and production. The book is chiefly intended for industry experts, professors, researchers, senior engineers, and enterprise managers.