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Reviews in Cardiovascular Pharmacology: 2023
Cardiovascular diseases are a principal cause of death globally. Cardiovascular diseases include hypertension, atherosclerosis, ischemic heart disease, and heart failure which cause a hike in socioeconomic burden. The disorders can occur due to unhealthy lifestyle like smoking and high-fat diet, genetic, and age. Both experimental and clinical studies are in progress, in search for drugs with improved efficacy and lesser side effects. These studies and experimental research aim to develop novel cardiovascular drugs, many of which are used clinically to alleviate the symptoms and severity of the diseases. For instance, combined therapy of sacubitril/valsartan for patients with heart failure d...
Pharmacoinformatics: New developments and challenges in drug design
Pharmacoinformatics combines bio- and chemoinformatics approaches as well as artificial intelligence to support drug design and development at various stages, starting from preclinical research support to clinical trial design and execution support (stages I, II and III), as well as pharmacovigilance, pharmacoeconomics and personalized medicine. The rational use of these methods, combined with the relevant experimental approaches, is crucial to face the new challenges in drug design and development.
Technical Aspects of Toxicological Immunohistochemistry
This authoritative volume examines immunohistochemical methods aimed at investigating the toxicologic pathology of rodent, non-human primate and aquatic animal tissues. Eleven comprehensive chapters provide pathologists and researchers in various sub-disciplines of toxicology with a comprehensive review of the methods and approaches for immunohistochemical staining in various target tissues. It explores the tissue-antigen and antibody-specific problems that may be encountered during the staining procedures and provide potential avenues for resolving various methodological issues. Special attention is paid to the latest enhancement procedures for antigen retrieval and visualization as well as image analysis and antigen quantification. Written by leading researchers in toxicology and pathology, this book is a significant resource for toxicologists and pathologists working with rodents, monkeys and aquatic animal tissues.
Exploring Traditional Wild Edible Plants
Wild edible plants are native species that grow and reproduce naturally in their natural habitats without domestication. These plants can serve as a healthier alternative to farmed crops that may be heavily laden with pesticides and other poisonous substances. This book focuses on assessment of the nutritional value, potential health benefits, and mechanisms of action of various wild edible plants. It presents information on nutrients and bioactive ingredients that can have health advantages, including antioxidant properties, antimicrobial, anti-inflammatory, and antidiabetic effects. Features: Comprehensive exploration of potential benefits as well as side effects of wild edible plants. Spe...
The Truth About Vegetable Oils and Your Health
The Truth About Vegetable Oils and Your Health", we uncover the often-overlooked health risks associated with the widespread use of vegetable oils in our diets. From soybean oil to sunflower oil, these seemingly harmless cooking staples have been linked to a host of health issues, including cardiovascular diseases, chronic inflammation, obesity, and even cancer. This comprehensive report delves into the science behind the dangers of vegetable oils, examining how industrial processing methods like refining, hydrogenation, and excessive heating can transform these oils into harmful substances. You'll discover how the overconsumption of omega-6 fatty acids, prevalent in many vegetable oils, can...
Lipid Peroxidation
The purpose of this book is to concentrate on recent developments on lipid peroxidation. The articles collected in this book are contributions by invited researchers with a long-standing experience in different research areas. We hope that the material presented here is understandable to a broad audience, not only scientists but also people with general background in many different biological sciences. This volume offers you up-to-date, expert reviews of the fast-moving field of Lipid Peroxidation. The book is divided in four mayor sections: 1-Lipid peroxidation: chemical mechanisms, antioxidants, biological implications; 2-Evaluation of lipid peroxidation processes; 3-Lipid peroxidation in vegetables, oils, plants and meats and 4-Lipid peroxidation in health and disease.
Overcoming Students' Misconceptions in Science
This book discusses the importance of identifying and addressing misconceptions for the successful teaching and learning of science across all levels of science education from elementary school to high school. It suggests teaching approaches based on research data to address students’ common misconceptions. Detailed descriptions of how these instructional approaches can be incorporated into teaching and learning science are also included. The science education literature extensively documents the findings of studies about students’ misconceptions or alternative conceptions about various science concepts. Furthermore, some of the studies involve systematic approaches to not only creating but also implementing instructional programs to reduce the incidence of these misconceptions among high school science students. These studies, however, are largely unavailable to classroom practitioners, partly because they are usually found in various science education journals that teachers have no time to refer to or are not readily available to them. In response, this book offers an essential and easily accessible guide.
