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The podocyte is a key cell that forms the last barrier of the kidney filtration unit. One of the most exciting developments in the field of nephrology in the last decade has been the elucidation of its biology and its role in the pathophysiology of inherited and acquired glomerular disease, termed podocytopathy. In this publication, world-renowned experts summarize the most recent findings and advances in the field: they describe the unique biological features and injury mechanisms of the podocyte, novel techniques used in their study, and diagnosis and potential therapeutic approaches to glomerular diseases. Due to its broad scope, this publication is of great value not only for clinical nephrologists and researchers, but also for students, residents, fellows, and postdocs.
Building on the success of the previous edition, this review book includes all of the original content plus several new chapters dedicated to the education and implementation of transthoracic echocardiography and point-of-care ultrasonography. Chapters feature board review-style questions and answers to assist readers with board exam preparation. This book also includes the most up-to-date echocardiography content and practice guidelines. This book fills an educational gap in the perioperative and critical care echocardiography landscape. It addresses essential perioperative and critical care echocardiography topics in an accessible manner for those who provide acute care and resuscitation in any environment, including the operating room, intensive care unit, and the emergency department. Essential Echocardiography, 2nd edition, is expertly written for the practitioner with limited knowledge of echocardiography preparing for either the Examination of Special Competence in Basic Perioperative TEE (Basic PTEeXAM) or the Examination of Special Competence in Critical Care Echocardiography (CCEeXAM).
This pocket-sized book is designed to provide up-to-date information for the general paediatrican and paediatric nephrologist, including advice on care of emergencies, chronic disorders and covering common and rare conditions. It is highly relevant for the day-to-day care of patients on the ward or in the outpatient clinic.
The New York Times–bestselling author of Unsinkable “recounts the disaster from the vantage point of nearby vessels” (Publishers Weekly). A few minutes before midnight on April 14, 1912, the “unsinkable” RMS Titanic, on her maiden voyage to New York, struck an iceberg. Less than three hours later, she lay at the bottom of the Atlantic Ocean. While the world has remained fascinated by the tragedy, the drama of those fateful hours was not only played out aboard the doomed liner. It also took place on the decks of two other ships, one fifty-eight miles distant from the sinking Titanic, the other barely ten miles away. The masters of the steamships Carpathia and Californian, Capt. Arth...
The main themes presented in this volume are exercise intolerance and muscle contracture. This comprehensive and updated volume allows neurologists, specialists in internal medicine, rheumatologists, pathologists, biochemists, physiatrists and all researchers interested in neuromuscular diseases to become familiar with many new and homogen data concerning exercise intolerance and muscle contracture.
This book aims to offer the accumulated fertile experience of treating drug-resistant epileptic patients collected over the past few decades, focusing on aspects of neurology, neurosurgery, emergency care, critical care medicine and basic medical research. Refractory status epilepticus is one of the most common severe and acute diseases in neurology and neurocritical care; it is also the main cause of death in epileptic patients. In the context of prevention and treatment processes, it is not only necessary to terminate epileptic seizures, but to also address the disruption of the patient’s internal environment and provide critical life support. Effective treatment calls for multi-discipli...
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On-line HDF represents a major technical development in the delivery of hemodialysis therapy: It combines the properties of increased diffusion available in current high-flux membranes with convective removal of between 6 and 30 liters per treatment and requires the use of ultrapure water and online filtration of replacement fluid. On-line HDF has been successfully introduced in Europe and Asia and is routinely prescribed for dialysis patients in these regions.The book at hand summarizes the history and achievements of on-line HDF in four parts: A report of the technological development in both machine and fiber/dialyzer is followed by a description of the challenges encountered in the evolution of on-line HDF, collecting the accounts of clinical key opinion leaders who had been involved in its early application. The third part presents a comprehensive review of the clinical results achieved with on-line HDF from its inception to the present times, in which it represents the clinical golden standard. The fourth and final part is dedicated to on-line HDF as a ‘vision’ for the future.