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Atopic dermatitis and psoriasis are common inflammatory skin diseases. The excellent therapeutic success of anti-IL-4/IL-13 biologics for atopic dermatitis and anti-TNF-α/IL-23/IL-17A biologics for psoriasis highlights the major pathogenic roles of these cytokines in the respective diseases. Although atopic dermatitis and psoriasis are distinct clinical entities, they share similar inflammatory processes, including increased Th17, Th22, and Th1 signatures. In addition to skin inflammation, both skin diseases exhibit a significant association with systemic diseases such as cardiovascular diseases, metabolic syndrome, and autoimmune diseases. In contrast to atopic dermatitis, males are more susceptible to psoriasis than females. Differential risk factors may be involved in the development and exacerbation in atopic dermatitis and psoriasis. In this issue, we will publish cutting-edge information regarding skin inflammation, clinical aspects, risk factors, microbiome, and therapeutics related to psoriatic and atopic inflammation.
More than 25 years have elapsed since the first application of immunofluorescent techniques in dermatology. These techniques have shed light on many problems concerning skin disorders. Microorganisms, antigens and antibodies, complements and enzymes have been observed in both intracellular and extracellular tissues. This is the first comprehensive atlas on dermato-immuno-histocytology; it collects the most outstanding studies and accompanying photographs carried out by 83 Japanese dermatologists.
A comprehensive review of all known immune mechanisms for medically important fungal pathogens from the organ perspectives of the human body. This authoritative guide is organized by organ system, as one particular fungus can have several different effects.
Why read Sustaining Seas? It is as simple as this: the seas sustain all life. This edited book emerges from conversations across several disciplines, and including practitioners of different specialities (artists, writers, planners, policy makers) about how to sustain the seas, as they sustain us. Sustaining Seas: Oceanic space and the politics of care aims to build a better understanding of what it means to care for aquatic places and their biocultural communities. The book is truly interdisciplinary and brings together a wide range of authors including, academics from diverse fields (architecture, science, cultural studies, law), artists, fisheries managers, and Indigenous Traditional Owne...
These Proceedings contain the contributions of the partIcIpants of the Third International Symposium on Dendritic Cells that was held in Annecy, France, from June 19 to June 24, 1994. This symposium represented a follow-up of the first and second international symposia that were held in Japan in 1990 and in the Netherlands in 1992. Dendritic cells are antigen-presenting cells, and are found in all tissues and organs of the body. They can be classified into: (1) interstitial dendritic cells of the heart, kidney, gut, and lung;(2) Langerhans cells in the skin and mucous membranes; (3) interdigitating dendritic cells in the thymic medulla and secondary lymphoid tissue; and (4) blood dendritic c...
This book is a printed edition of the Special Issue "Antioxidants in Health and Disease" that was published in Nutrients
Be sure your skin-care treatments have strong evidential support Evidence-based Dermatology, Third Edition takes a unique approach to clinical dermatology by emphasising use of only the highest quality available evidence when treating people with skin diseases. Beginning with a toolbox introduction to the practice of evidence-based dermatology, it then covers the application of evidence for dermatological treatments across a wide range of ailments, including: • Common inflammatory skin diseases • Skin cancer, moles and actinic keratoses • Infective skin disease, exanthems and infestations • Disorders of pigmentation In addition, many of the rarer skin disorders are also included so a...