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Molecular Mechanisms of Cilia Related Diseases
Eukaryotic cilia are evolutionarily conserved microtubule-based structures that protrude from the cell surface. In vertebrates, multiple motile and primary (immotile) cilia fulfill sensory and motility functions that are critical for embryonic development and the homeostasis of adult tissues. Cilia malfunction has been shown to cause a growing number of diseases presenting phenotypes such as brain and skeletal developmental problems, intellectual disability, blindness, infertility, obesity, and kidney cysts. Despite their clinical relevance, we are still far from fully understanding the basic biology of these multiple cilia types. For example, we do not know the molecular compositions of all...
Ethical Exchanges in Translation, Adaptation and Dramaturgy
Ethical Exchanges in Translation, Adaptation and Dramaturgy examines compelling ethical issues that concern practitioners and scholars in the fields of translation, adaptation and dramaturgy. Its 11 essays, written by academic theorists as well as scholar-practitioners, represent a rich diversity of philosophies and perspectives, and reflect a broad international frame of reference: Asia, Europe, North America, and Australasia. They also traverse a wide range of theatrical forms: classic and contemporary playwrights from Shakespeare to Ibsen, immersive and interactive theatre, verbatim theatre, devised and community theatre, and postdramatic theatre. In examining the ethics of specific artistic practices, the book highlights the significant continuities between translation, adaptation, and dramaturgy; it considers the ethics of spectatorship; and it identifies the tightly interwoven relationship between ethics and politics.
Comparative Cultural Studies and Latin America
The genesis of Comparative Cultural Studies and Latin America stems from the contributors' conviction that, given its vitality and excellence, Latin American literature deserves a more prominent place in comparative literature publications, curricula, and disciplinary discussions. The editors introduce the volume by first arguing that there still exists, in some quarters, a lingering bias against literature written in Spanish and Portuguese. Secondly, the authors assert that by embracing Latin American literature and culture more enthusiastically, comparative literature would find itself reinvigorated, placed into productive discourse with a host of issues, languages, literatures, and cultur...
BOWIE et al. v. WHEELWRIGHT (1821)
File No. 1011
6th International Conference on Practical Applications of Computational Biology & Bioinformatics
The growth in the Bioinformatics and Computational Biology fields over the last few years has been remarkable and the trend is to increase its pace. In fact, the need for computational techniques that can efficiently handle the huge amounts of data produced by the new experimental techniques in Biology is still increasing driven by new advances in Next Generation Sequencing, several types of the so called omics data and image acquisition, just to name a few. The analysis of the datasets that produces and its integration call for new algorithms and approaches from fields such as Databases, Statistics, Data Mining, Machine Learning, Optimization, Computer Science and Artificial Intelligence. W...
World Literature in Theory
World Literature in Theory provides a definitive exploration of the pressing questions facing those studying world literature today. Coverage is split into four parts which examine the origins and seminal formulations of world literature, world literature in the age of globalization, contemporary debates on world literature, and localized versions of world literature Contains more than 30 important theoretical essays by the most influential scholars, including Johann Wolfgang von Goethe, Hugo Meltzl, Edward Said, Franco Moretti, Jorge Luis Borges, and Gayatri Spivak Includes substantive introductions to each essay, as well as an annotated bibliography for further reading Allows students to understand, articulate, and debate the most important issues in this rapidly changing field of study
Top Girls
Marlene thinks the eighties are going to be stupendous. Her sister Joyce has her doubts. Her daughter Angie is just frightened. Since its premiere in 1982, Top Girls has become a seminal play of the modern theatre. Set during a period of British politics dominated by the presence of the newly elected Prime Minister Margaret Thatcher, Churchill's play prompts us to question our notions of women's success and solidarity. Its sharp look at the society and politics of the 1980s is combined with a timeless examination of women's choices and restrictions regarding career and family. This new Student Edition features an introduction by Sophie Bush, Senior Lecturer at Sheffield Hallam University, UK...
Sulfur-Containing Marine Bioactives
Sulfur is an essential element for all living organisms and is required by algae, plants, fungi, animals, and humans for growth and development. It is present in a variety of biomolecules involved in many biological functions, including the maintenance of cell redox homeostasis, defense, and detoxifying processes. The alteration of sulfur compound metabolism may lead to human diseases as well as to plant and animal pathologies. The marine environment, which is characterized by a high biodiversity of species and a great chemical diversity, represents a great potential source of bioactive sulfur molecules. A broad range of biologically active sulfur compounds with unique structures and pharmacological properties have been reported to occur in marine organisms, from amino acids to different sulfated derivatives. Great attention is also focused on sulfur metabolites in the marine microbial world in relation to the global sulfur cycle. The aim of this Special Issue is to present existing knowledge and recent studies on sulfur-containing marine bioactive compounds in different biological systems. Attention is also focused on metabolites active at the ecological level.
