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Trusted for more than 40 years and updated to reflect today’s nursing challenges, Porth’s Pathophysiology: Concepts of Altered Health States, 11th Edition, continues a legacy of excellence with a comprehensive, nursing-focused approach that instills a mastery of both the physical and psychological aspects of altered health. More approachable and inclusive than ever, this unique text clarifies complex ideas through diverse perspectives, the latest evidence-based information, and engaging in-text features and application exercises.
"As you have grown older, you may have noticed changes in your memory. You might find yourself walking into a room and forgetting why you are there. It might be more difficult to remember the name of someone you just met. You may also notice that it takes longer to come up with words in conversation"--
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Nanohybrid Fungicides: Novel Applications in Plant Pathology addresses the opportunities that nano-based fungicides have in Agriculture.Broken into two parts, this book addresses sustainable alternative in fungal plant diseases management, nanoencapsulation applications in fungicides, nano/biofungicides for controlling fungal plant pathogens, and applications. commercialization and remediation of nano fungicides in plant diseases control.Plant scientists, agriculture and food scientists, as well as professionals and students working in related fields will all benefit from this timely resource.• Explains the role of nanohybrid fungicides in agriculture• Addresses nanoencapsulation applications in fungicides• Explores antifungal potential of Nano and Micro-encapsulated phytochemical compounds• Includes the general applications. commercialization and remediation of nanohybrid fungicides
The first real major breakthrough that laid the basis of HLA antibody detection in the field of solid organ transplantation, came with the introduction of the complement dependent cytotoxicity (CDC) test in 1964 by Terasaki and McClelland. Since then, methods for antibody detection have evolved remarkably from conventional cell-based assays to the current advanced solid phase systems on the Luminex platform, with increasing degree of sensitivity and specificity. The latter have been indispensable for more accurate identification of donor specific HLA antibodies in broadly reactive allo antisera, and to guide donor selection and kidney paired exchange programs through virtual crossmatching, i...
Computational methods have become an indispensible tool for elucidating the mechanism of organometallic reactions. This snapshot of state-of-the-art computational studies provides an overview of the vast field of computational organometallic chemistry. Authors from Asia, Europe and the US have been selected to contribute a chapter on their specialist areas. Topics addressed include: DFT studies on zirconium-mediated reactions, force field methods in organometallic chemistry, hydrogenation of π-systems, oxidative functionalization of unactivated C-H bonds and olefins, the osmylation reaction, and cobalt carbonyl clusters. The breadth and depth of the contributions demonstrate not only the crucial role that computational methods play in the study of a wide range of organometallic reactions, but also attest the robust health of the field, which continues to benefit from, as well as inspire novel experimental studies.
A comprehensive review of the recent developments in DNA repair research that have potential for translational applications. The book explains in detail the various biological mechanisms by which cancer cells can circumvent anticancer therapy and limits its usefulness in patients. They also review the impact of such novel inhibitors of DNA repair mechanisms as methylguanine-DNA-methyltransferase. Also examined are inhibitors of other DNA repair enzymes such as PARP and DNA-PK. The book captures-for both cancer researchers and oncologists dealing with hallmark "relapse" or "drug resistance" phenomena on a daily basis-the many exciting new uses of DNA repair inhibitors, either alone or in combination with anticancer therapies.