Welcome to our book review site go-pdf.online!
You may have to Search all our reviewed books and magazines, click the sign up button below to create a free account.
Atmospheric Chemistry in the Mediterranean Region
This two-volume set provides an extensive review of the abundant past and recent literature on the atmospheric chemistry in the Mediterranean region. The books document the experience gained on the atmospheric composition over the Mediterranean basin and close areas after almost six decades of studies, starting from early studies of radioactive aerosol fallouts and intense desert dust events in the 1960s, aerosol samples collected during oceanographic cruises in the early 1980s and including discoveries from subsequent surface monitoring stations, intensive campaigns, satellite climatologies, laboratory studies, as well as chemistry-transport and climate models. Through ten thematic sections...
The Functional Nucleus
This book gives an in-depth overview on nuclear structure and function. It clearly shows that the epigenome and the three-dimensional organization of the nucleus are not independent properties. The intimate relationship between the location and the epigenetic modifications of gene loci is highlighted. Finally, it shows that the complex three-dimensional organization of the nucleus is not just of academic interest: The structure, composition and function of virtually all of the sub-nuclear compartments identified so far can be implicated to a list of human genetic diseases. Hence, a detailed elucidation of how these domains are assembled and function will provide new opportunities for therapeutic intervention in clinical practice.
Controllability of Dynamic Systems
The book is about the possibilities of involvement of the well-known Green’s function method in exact or approximate controllability analysis for dynamic systems. Due to existing extensions of the Green’s function notion to nonlinear systems, the approach developed here is valid for systems with both linear and nonlinear dynamics. The book offers a number of particular examples, covering specific issues that make the controllability analysis sophisticated, such as coordinate dependent characteristics, point sources, unbounded domains, higher dimensions, and specific nonlinearities. It also offers extensive numerical analysis, which reveals both advantages and drawbacks of the approach. As such, the book will be of interest to researchers interested in the theory and practice of control, as well as PhD and Master’s students.
The Making of Medieval Sardinia
This landmark volume combines classic and revisionist essays to explore the historiography of Sardinia’s exceptional transition from an island of the Byzantine empire to the rise of its own autonomous rulers, the iudikes, by the 1000s. In addition to Sardinia’s contacts with the Byzantines, Muslim North Africa and Spain, Lombard Italy, Genoa, Pisa, and the papacy, recent and older evidence is analysed through Latin, Greek and Arabic sources, vernacular charters and cartularies, the testimony of coinage, seals, onomastics and epigraphy as well as the Sardinia’s early medieval churches, arts, architecture and archaeology. The result is an important new critique of state formation at the margins of Byzantium, Islam, and the Latin West with the creation of lasting cultural, political and linguistic frontiers in the western Mediterranean. Contributors are Hervin Fernández-Aceves, Luciano Gallinari, Rossana Martorelli, Attilio Mastino, Alex Metcalfe, Marco Muresu, Michele Orrù, Andrea Pala, Giulio Paulis, Giovanni Strinna, Alberto Virdis, Maurizio Virdis, and Corrado Zedda.
Retinoids in Oncology
This reference provides a comprehensive overview of recent developments in basic research that are relevant to the application of retinoids for cancer prevention and treatment.;Organized in a quick-referral format by specific disease site, this book: describes the effects of retinoids on squamous differentiation in normal, pre-malignant, and malignant epithelial tissues; addresses the mechanisms by which cultured keratinocytes respond to retinoids; considers the antitumor activity of combination therapy with retinoids and cytokines; reviews the toxicity profiles of the vitamin A molecule and the synthetically derived retinoid compounds and their effects on humans; examines the use of retinoi...
Targeted Therapies in Oncology
Since the last edition of this book, major advances have been made in our understanding of key pathways that control tumor progression. This has led to the development of new anticancer agents that have the ability to block the activity of proteins involved in neoplastic cell development and proliferation. Targeted Therapies in Oncology, Second Edi
Clinical Ocular Pharmacology
Clinical Ocular Pharmacology, Second Edition covers the diagnostic and therapeutic clinical procedures in the administration of drugs to the eye. This book is organized into five parts encompassing 35 chapters that evaluate the basic pharmacologic principles that govern the different types of ophthalmic drugs. It addresses the pharmacologic agents useful in the diagnosis and treatment of ocular diseases. Some of the topics covered in the book are the basic science of ocular pharmacology; clinical administration of ocular drugs; drugs affecting the autonomic nervous system; types of local anesthetics; review of anti-inflammatory drugs; and examination of inhibitors of aqueous formation. Other parts deal with the development of contact lens solution in clinical practice and the pharmacologic management of strabismus. These topics are followed by discussions of the legal basis of using drugs in optometry and the systemic effects of ocular drugs. The concluding part is devoted to the diseases of the optic nerve. The book can provide useful information to doctors, optometrists, pediatricians, students, and researchers.
Endothelium
The function and life span of endothelial cells have a large impact upon the quality and expectancy of an individual's life. During low perfusion, the adaptation of different cells to hypoxia precipitate the aggressive progression of diseases. Although the clinical studies have convincingly shown that endothelial dysfunction occurs whenever the biological functions or bioavailability of nitric oxide are impaired, in all these scenarios, the role of endothelial cell-destructive process cross-talk is yet poorly understood. This book focuses on the contribution of molecular mechanisms to endothelial dysfunction in related metabolic disorders.
Advances in Targeted Cancer Therapy
There have been tremendous advances in our understanding of molecular and tumor biology during the past few years. In the field of cancer therapeutics, it is expected that cytotoxic drug approaches will be gradually replaced with treatments based on biological targeted approaches. Hopefully these new targeted therapies will significantly increase efficacy and lack the devastating and troublesome side effects elicited by cytotoxic chemotherapy. This volume is the first book to cover the general topic of targeted cancer therapy. It presents a range of targets such as tumor angiogenesis, cell cycle control and cell signalling, COX-2, apoptosis/cell survival, invasion and metastasis and approach...
Knowledge Engineering and Knowledge Management
This book constitutes the refereed proceedings of the 21th International Conference on Knowledge Engineering and Knowledge Management, EKAW 2018, held in Nancy, France, in November 2018. The 36 full papers presented were carefully reviewed and selected from 104 submissions. The papers cover all aspects of eliciting, acquiring, modeling, and managing knowledge, the construction of knowledge-intensive systems and services for the Semantic Web, knowledge management, e-business, natural language processing, intelligent information integration, personal digital assistance systems, and a variety of other related topics. A special focus was on "Knowledge and AI", i.e. papers describing algorithms, tools, methodologies, and applications that exploit the interplay between knowledge and Artificial Intelligence techniques, with a special emphasis on knowledge discovery.
