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Immunology of Ocular Tumors
The eye and the ocular adnexa may give rise to over three hundred histologically different tumors - by far the largest tumor variety of the human body. However, the immunological behavior of these tumors has only been explored in some cases, although it is well established that the eye is an immune-privileged site in which cells that express foreign antigens escape immune-mediated elimination. Human tumors also create an immune-privileged surrounding and thereby escape from anti-tumor immune responses. Highlighting aspects of ocular and general tumor, this text summarizes the role of the immune system and how tumor tissue can influence various parameters (T-cells, NK-cells, HLA-expression, apoptosis), leading to escape mechanisms used by the tumor. New therapeutic regimens urgently required by patients are also reviewed, and the immunological behavior of skin melanoma is compared to choroidal melanoma, whilst basal cell carcinoma of the ocular lid is compared to those of the skin.
Neurochemistry
Compiles 195 contributions from the June 1996 meeting. Part I (clinical aspects and pathology) discusses the role of neuroprotection and neurorescue in ischemia, stroke, and neuronal injury, as well as neurochemical mechanisms, mood disorders, and the significance of cerebrospinal fluid examinations for diagnosis and treatment. Part II (cellular functions) covers nutrient transport, energy metabolism, and metabolic trafficking in brain cells, and the role of neurotrophic molecules. Part III (molecules/methods) describes functional aspects of neuroactive compounds, with a special focus upon acetylocholine, taurine, amino acid neurotransmitters, and neuropeptides. Also discusses the role of lipid mediators, brain proteins, and new insights in methodology. Annotation copyrighted by Book News, Inc., Portland, OR
The Code
Jarred, a CIA assassin is on a covert assignment in Africa to stop development of a genocidal virus. Then he gets caught up in a second mission when the virus appears in Germany. He teams up with a sniper and Peter Cahill, a retired New York Police Detective. Jarred realizes they are on the right track when he too becomes the hunted in this global whirlwind search and destroy mission for a virus, its creator, and a corrupt clandestine power surging closer to its goal.
Combination Therapies
Over the past decade many of the key lymphokines, hormones and growth factors that help regulate the immune system have been defined. These molecules, termed biological response modifiers (BRMs) , have been sequenced, synthesized and produced in large enough quantities to test in animals and humans resulting in the development of new approaches to the treatment of human disease, in particular, cancers and infectious diseases. Advances in this area have also led to rethinking therapies against a range of autoimmune disorders and other diseases associated with immune and endocrine imbalances. BRMs currently are being applied clinically as both primary and adjunctive therapy to enhance the effe...
Research on Gender and Sexualities in Africa
This collection comprises a diverse and stimulating collection of essays on questions of gender and sexualities, crafted by both established and younger researchers. The collection includes fascinating insights into topics as varied as the popularity of thong underwear in urban Kenya, the complexity of Tanzanian youth’s negotiation of HIV-cultures, the dialogues between religion and controversial questions in sexualities activism, and the meaning of living as a Zimbabwean girl, who became HIV-positive because her mother had no access to antiretroviral drugs during pregnancy. Some pieces deepen contemporary debates, others initiate new questions. The collection seeks to sustain and invigorate research, policy-making and continentaly-focused thought on difficult, yet compelling, realities.
The Valley's of Life
This is the story of young girl from Tanzania. Her struggles through life. She started out wanting to be a nun. But her experience with nuns who runs the college put her off. A poor young girl goes to college away from home, left to fend for herself. Through hardiship and traumatic life, how the young beautiful woman struggles against male domination.
