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Deadenylation
  • Language: en
  • Pages: 326

Deadenylation

This volume provides new approaches and technologies into roles of poly(A) metabolism in translation, RNA stability, and quality control of gene expression. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Deadenylation: Methods and Protocols aims to pave the way for future investigations of the complex regulatory networks that control mRNA stability and expression.

Post-transcriptional Mechanisms in Endocrine Regulation
  • Language: en

Post-transcriptional Mechanisms in Endocrine Regulation

  • Type: Book
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  • Published: 2016-01-08
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  • Publisher: Springer

This book examines how post-transcriptional mechanisms control endocrine function. This includes newly identified regulatory mechanisms involved in hormone biosynthesis, control of hormone receptors and the outputs of hormone mediated signal transduction. Chapters address endocrine hormones including protein peptide/peptide, steroid, and non-steroidal hormones. The impacts of these mechanisms on disease and health are covered, providing a novel update to the scientific literature. Post-transcriptional regulatory mechanisms play an essential role in controlling dynamic gene expression. The outcome of this regulation includes control of the amount, timing, and location of protein expression. Regulation is mediated by cis-acting RNA sequences and structures and transacting RNA binding proteins and non-coding RNAs, including microRNAs. Recent advances in characterization of these regulatory factors have revealed enormous regulatory potential.

RNA Turnover in Eukaryotes: Nucleases, Pathways and Analysis of mRNA Decay
  • Language: en
  • Pages: 661

RNA Turnover in Eukaryotes: Nucleases, Pathways and Analysis of mRNA Decay

Specific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, RNA folding, as well as the translation of genetic information from mRNA into protein sequences. Messenger RNA (mRNA) decay is now emerging as an important control point and a major contributor to gene expression. Continuing identification of the protein factors and cofactors, and mRNA instability elements responsible for mRNA decay allow researchers to build a comprehensive picture of the highly orchestrated processes involved in mRNA decay and its regulation. - Covers the nonsense-mediated mRNA decay (NMD) or mRNA surveillance pathway - Expert researchers introduce the most advanced technologies and techniques to identify mRNA processing, transport, localization and turnover, which are central to the process of gene expression - Offers step-by-step lab instructions, including necessary equipment and reagents

Post-transcriptional Mechanisms in Endocrine Regulation
  • Language: en
  • Pages: 347

Post-transcriptional Mechanisms in Endocrine Regulation

  • Type: Book
  • -
  • Published: 2015-12-30
  • -
  • Publisher: Springer

This book examines how post-transcriptional mechanisms control endocrine function. This includes newly identified regulatory mechanisms involved in hormone biosynthesis, control of hormone receptors and the outputs of hormone mediated signal transduction. Chapters address endocrine hormones including protein peptide/peptide, steroid, and non-steroidal hormones. The impacts of these mechanisms on disease and health are covered, providing a novel update to the scientific literature. Post-transcriptional regulatory mechanisms play an essential role in controlling dynamic gene expression. The outcome of this regulation includes control of the amount, timing, and location of protein expression. Regulation is mediated by cis-acting RNA sequences and structures and transacting RNA binding proteins and non-coding RNAs, including microRNAs. Recent advances in characterization of these regulatory factors have revealed enormous regulatory potential.

RNA Recognition
  • Language: en
  • Pages: 470

RNA Recognition

RNA Recognition, Volume 623, the latest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This updated volume covers a variety of topics, including The Preparation of cooperative RNA recognition complexes for crystallographic structural studies, Methods for thermal denaturation studies of fluorogenic aptamers, Dynamic combinatorial chemistry as a rapid, fragment-based approach to RNA-targeted compound discovery, Using a click chemistry assay to identify natural product ligands for pre-microRNAs, Lessons from exploration of chemical and structural small molecule:RNA space, Using ligand-observed NMR to study RNA-small molecule interactions, and much more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Methods in Enzymology series - Includes the latest information on RNA Recognition

Proceedings of the National Academy of Sciences of the United States of America
  • Language: en
  • Pages: 1140

Proceedings of the National Academy of Sciences of the United States of America

  • Type: Book
  • -
  • Published: 2000
  • -
  • Publisher: Unknown

None

Meeting of Board of Regents
  • Language: en
  • Pages: 362

Meeting of Board of Regents

  • Type: Book
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  • Published: 2009-11
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  • Publisher: Unknown

None

Bellefonte, State College and Nearby Points Telephone Directory
  • Language: en
  • Pages: 622

Bellefonte, State College and Nearby Points Telephone Directory

  • Type: Book
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  • Published: 1994
  • -
  • Publisher: Unknown

None

Techniques of Autoradiography
  • Language: en
  • Pages: 338

Techniques of Autoradiography

  • Type: Book
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  • Published: 1969
  • -
  • Publisher: Unknown

None

A Dictionary of German-Jewish Surnames
  • Language: en
  • Pages: 832

A Dictionary of German-Jewish Surnames

This dictionary identifies more than 13,000 German-Jewish surnames from the area that was pre-World War I Germany. From Baden-Wuerttemburg in the south to Schleswig-Holstein in the north. From Westfalen in the west to East Prussia in the east. In addition to providing the etymology and variants of each name, it identifies where in the region the name appeared, identifying the town and time period. More than 300 sources were used to compile the book. A chapter provides the Jewish population in many towns in the 19th century.