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Chromosomal Alterations
Due to sensitive molecular biological techniques, our understanding of chromosomal aberrations is steadily increasing. Provided here is a review of basic and applied aspects of the field. Chromosome structure, induction of DNA lesions by different clastogenic agents and their repair, induction of aberrations by agents which affect specific sequences in the DNA, and factors affecting induction and yield of chromosomal aberrations are covered. Further, topics such as automation of aberration scoring, problems associated with using chromosomal aberrations and micronuclei in population monitoring and the importance of chromosomal aberration assays in mutagenicity testing of chemicals are included.
DNA Repair and Human Disease
DNA Repair and Human Disease highlights the molecular complexities of a few well-known human hereditary disorders that arise due to perturbations in the fidelity of diverse DNA repair machineries.
Environmental Carcinogenesis
Environmental Carcinogenesis, Volume 96 in the Advances in Pharmacology series, reports on work done with carcinogenic metals and the mechanisms of their carcinogenicity, including Arsenic and Chromate. Chapters in this release include Breast cancer carcinogenesis by organophosphate pesticides, Polyadenylation of Canonical histone H3.1 in Carcinogenesis, Epigenomic reprogramming in iAs-mediated carcinogenesis, MicroRNAs and epigenetic regulation in metal-induced angiogenesis and carcinogenesis, Environmental epigenetics and new mechanistic markers of chemical exposure, Arsenic carcinogenesis by inhibition of DNA repair, Genetic and environmental reprogramming of the sarcoma epigenome, Mechanism of chromate carcinogenesis by chromatin alterations, and more. Other chapters cover Arsenic carcinogenesis and microRNAs, Epigenetic mechanism of Cr(VI)-induced cell malignant transformation and tumorigenesis, The dark side of NRF2 in arsenic carcinogenesis, and Chemical mechanisms of DNA damage by carcinogenic chromium(VI). Covers metal carcinogens Includes discussions on the mechanisms of cancer formation Provides updates on the diverse mechanisms that drive cancer formation by metals
The Minimum Method
When it comes to looking and feeling your best, less really can be more. Discover how to maximize your sleeping, eating, exercising—even thinking and breathing—with minimum effort. The truth is most people don’t actually need grueling, extreme workouts or aggressively limited diets to lose weight and feel proud to flaunt their bodies in bathing suits. What they need is a plan that is focused on efficiency—the best results for the least amount of time and effort—and one that is actually designed to be maintained for more than 30 days. In The Minimum Method, by nutrition expert and celebrity fitness trainer Joey Thurman, you’ll learn a wealth of practical advice, simple nutrition t...
Nature
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Cancer Research
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