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Deutschland
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Congressional Record
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Endocrine Abnormalities and Renal Complications
Vertebrate kidneys play a vital role in regulating body homeostasis, in addition to being instrumental in preventing large blood molecules from filtering out into the urine. Several endocrine factors have an influential role in renal health. Hormones are necessary for the normal health of the kidney and altered levels of them are harmful to glomerular health, manifesting in chronic kidney disease and proteinuria. Recent evidence attributes novel roles to several endocrine mediators in renal biology, including growth hormone, thyroxine, and glucocorticoids. In recent times, researchers have demonstrated altered levels of these hormones elicit a decline in renal function by afflicting several cellular and molecular manifestations in specific renal cells. More research is needed to better understand this connection and its potential translational implications.
