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Archibald Garrod and the Individuality of Man
Students of biology learn that Archibald Garrod (1857-1936) advanced the concept of inborn errors of metabolism through brilliant insights into patients with rare genetic diseases. Garrod's two other prescient concepts are often overlooked: (1) the concept of the chemical uniqueness of the individual, which prefigured the modern appreciation of individual predisposition to disease; & (2) the concept of the physician-scientist, which prefigured the modern revolution in biomedical research. All three concepts are brought into sharp focus in this incisive biography, written devotedly by Alexander G. Bearn, a disciple whose own career is based firmly on the Garrodian tradition. Illustrations.
Sir Clifford Allbutt
Monograph looking at the life of Sir Clifford Allbutt, inventor of the short themometer and responsible for introducing the opthalmoscope, weighing machine and microscope to the wards.
Useful Knowledge
Useful Knowledge: What will it be for the next millennium? In five symposia, members of the Amer. Philosophical Soc. asked this question in April 1999 at the Society's Millennium Meet. Contents: (1) Math & Physical Sciences: The Laws of Nature; Our Concepts of the Cosmos, Progress, Prospects & Mysteries; Math & Computing; Global Warming: Does Science Matter?; & The Molecular Biology of Huntington's Disease; (2): Biological Sci.: Scientists & the Public: An Ambivalent Partnership; Cancer: The Revolution & the Challenges; Wiring the Brain: Dynamic Interplay between Nature & Nurture; & A Neuroscience of Memory for the 21st Cent.; (3) Social Sci.: Nat. Sovereignty & Human Rights; Econ. Becomes a Science -- Or Does It?; & A Millennium of Economics in Twenty Minutes: In Pursuit of Useful Knowledge; (4) Humanities: Art & Architectural History in the 20th Cent.; More Than One Millennium: The Perennial Return of the History of Religions; & Singularity in an Age of Globalization; & (5) The Professions, Arts & Affairs: 100 Yrs. of the Renaissance; Race & Admission to Univ.; Health Care in a Democratic Soc.; & Culture & Democracy in America. Illus.
Progress in Medical Genetics
Progress in Medical Genetics: Volume 5 covers the improvements in nutrition and control of childhood disease. This book is divided into five chapters that evaluate the characteristics of thalassemias, an inherited defect in hemoglobin. It addresses the genetic control of hemoglobin synthesis and the clinical pictures and nomenclature of the different porphyrias. Some of the topics covered in the book are the genetic aspects of liver disease connected with jaundice; development of the concept of thalassemia as a hemoglobinopathy; bilirubin metabolism; description of hemolytic jaundice; description of hyperbilirubinemia. The succeeding chapters describe the disturbances in bilirubin uptake and conjugation, as well as the clinical diagnosis of familial non-hemolytic hyperbilirubinemias. An analysis of the Dubin-Johnson and Rotor syndrome is provided. The last chapters consider the genetics of muscular and the analysis of autosomal dominant forms of muscular dystrophy. The book can provide useful information to doctors, endocrinologists, students, and researchers.
Sir Francis Fraser, 1885-1964
Born in Edinburgh in 1885, Sir Francis Fraser helped revolutionise medical education and nurtured generations of researchers and practitioners in the wake of World War II, throughout which he directed the nation's emergency medical services. This book surveys the career of this energetic and formidable Scotsman.
Genetics of Neurological Disorders
The seven research papers contained in this volume report the latest and most important findings on topics in genetics that are related to medical practice. In particular the contributions focus on genetic aspects of specific kinds of disorders, including epilepsy, muscular dystrophies, and Huntington's disease. The book as a whole attests to the growing importance of genetic expertise in the day-to-day practice of medicine.
