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Targeted Therapies
This volume explores the mechanisms of resistance to targeted therapeutics. The focus is on the cancer cell signaling network, although other mechanisms of resistance including target mutation, and new areas of study such as cancer stem cells are included. Targeted Therapies: Mechanisms of Resistance highlights examples of changes in the signaling network in response to inhibition of a signaling event and underscores the importance in having a mechanistic understanding of the signaling network in cancer for developing effective targeted cancer therapies. Moreover, cutting edge tools to analyze the cell signaling network will be discussed. This includes the leading edge of techniques as well as computational biology and systems theory. This volume provides the reader with both an overview as well as a detailed perspective on the mechanisms of resistance to targeted therapeutics and will be of great value to the oncologist, the physician-scientist treating patients and the translational scientist working on any aspect of targeted therapeutics.
Behavioral Medicine
This ambitious book provides the latest research in leading topics of behavioral medicine and evidence-based strategies for its application in solving clinical problems. Each of the book’s clinical chapters, covering a breadth of topics from doctor-patient communication to patient adherence, preparation for surgery and cancer, begins with a clinical case study that guides the reader through the chapter. The author expertly takes the reader through relevant background information, including the epidemiology and medical background of the disease, the psychological predictors of onset or prognosis in the condition, and relevant psychological interventions. The chapters conclude by revisiting ...
AACR 2022 Proceedings: Part A Online-Only and April 10
The AACR Annual Meeting is the focal point of the cancer research community, where scientists, clinicians, other health care professionals, survivors, patients, and advocates gather to share the latest advances in cancer science and medicine. From population science and prevention; to cancer biology, translational, and clinical studies; to survivorship and advocacy; the AACR Annual Meeting highlights the work of the best minds in cancer research from institutions all over the world.
Emerging Topics and Questions in Infocommunication Technologies
This collection of essays consists of selected papers presented at the 24th IEEE FRUCT conference. It highlights the most pressing research topics in infocommunication technologies, such as challenges in the development of next generation networks, the architectures and design of innovative knowledge-based systems, and innovations in healthcare and eHealth.
Biennial Report
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Etude des mécanismes de résistances primaire et acquise aux inhibiteurs du récepteur de l'Epidermal Growth Factor dans le cancer bronchique non à petites cellules
Les inhibiteurs de tyrosine kinase (ITK) du récepteur à l'Epidermal Growth Factor (EGFR) constituent un nouveau traitement du cancer bronchique non à petites cellules (CBNPC), particulièrement efficace chez les patients porteurs d'une mutation d'EGFR (EGFR M+). Néanmoins, certains de ces patients peuvent avoir une résistance primaire à ces traitements, et les autres développent inéluctablement une rechute correspondant au phénomène de résistance acquise. L'objectif de ce travail était d'étudier les mécanismes de résistances primaire et acquise chez les patients avec CBNPC EGFR M+.Nous avons montré que le statut mutationnel de KRAS était le même dans la tumeur primitive et ...
International Agency for Research on Cancer Biennial Report 2006-2007
A wide range of projects are described in the latest Biennial Report of the International Agency for Research on Cancer (IARC), the cancer research branch of the World Health Organization. Most of these projects involve collaborations with scientists in institutes throughout the world, covering topics ranging from descriptive epidemiology and biostatistics, cancer registration and analysis of data on cancer occurrence, to basic research on genetic and molecular aspects of cancer development to pathogenesis and prevention studies. Profusely illustrated, the Report also contains details of the personnel and organization of IARC and its activities, as well as a complete list of over 500 publications and articles authored by its scientists and their collaborators during the biennium.
Pneumologie
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