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What happens when a pastor gets depressed? When Alfred Lam fell into a deep depression, all that mattered to him was quelling the pain. He did not care about "right" or "wrong" - he just wanted the pain to stop. Told with brutal honesty, this is the inspiring story of one pastor's journey through the abyss of depression. When his life finally hit rock bottom, he realized that everything had to change - including an overhaul of his faith and beliefs.
A descriptively annotated, multidisciplinary, cross-referenced and extensively indexed guide to 2,395 dissertations that are concerned either in whole or in part with Hong Kong and with Hong Kong Chinese students and emigres throughout the world.
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This book comprehensively reviews the role of cancer stem cells (CSCs) in cancer initiation, progression, and resistance to anticancer therapies. The initial chapters examine the methods and procedure of the detection, isolation, and characterization of CSCs. It also introduces various epigenetic pathways that contribute to cancer initiation and tumorigenesis, particularly regarding the maintenance and survival of CSCs. It also explores the role of CSCs metabolism and the mechanisms of metabolic plasticity of CSCs in cancer biology. Further, it also presents the implications of CSCs on the origin of tumor heterogeneity and on heterogeneity of the therapeutic response. Towards the end, this book highlights the different immunotherapeutic approaches targeting CSCs with the potential of strongly improving cancer outcomes. This book offers a broad framework to scientists and clinicians into the state-of-the-art knowledge on cancer stem cell biology and highlights their therapeutic implications.
In People of Paradox, Terryl Givens traces the development of Mormon culture from the days of Joseph Smith in upstate New York, to the global spread of the Latter-Day Saints. Here is a religion shaped by an authoritarian hierarchy and individualism, intellectual investigation, existence in exile and a yearning for acceptance by the larger world.
Reprint of the original, first published in 1874.