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Biosimilars and Generic Medications in Ophthalmology
In this book, the authors present the history of generic drug development, FDA and European Medecines Agency (EMA) requirements for generic drug entry, a comparison of generic and branded drugs, concerns around generic ophthalmic drugs, the issues of costs of generic and branded drugs, and issues as well as perceptions regarding the clinical use and acceptance of generic drugs among the patients, prescribers, and pharmacists. In addition to the previous edition, a chapter has been added about biosimilars.
Glaucoma Research and Clinical Advances
Foreword Volume 2 of our serial publication continues our desire to address glaucoma with a combination of science and speculation. As science expands, the emphasis is on data, interpretation, and dogma. We disagree; open minds open new approaches. Using methodologies that are primarily molecular and genetic, we seek to refine the causes of glaucoma as well as how it is best treated, especially incorporating thoughts and hypotheses about new methods of treatment. Glaucoma is a complex disease, and genetics proves that a variety of proteins are culpable at one level. At another level, however, there are likely final common pathways and numerous feedback loops which have defied explanations to...
Intraocular and Intracranial Pressure Gradient in Glaucoma
This book focuses on the characteristic of glaucomatous optic neuropathy and its relationship with cerebrospinal fluid (CSF) pressure. It also explores the potential novel methods to manage glaucoma by adjusting CSF pressure. This book covers several interesting topics such as why normal tension glaucoma (NTG) patients still develops into glaucoma without high intraocular pressure (IOP); and whether there are factors other than IOP contributing to the pathogenesis of NTG why the role of IOP in the pathogenesis of POAG becomes vague and controversial. This book contains over 40 chapters, including numerous images from clinical patients and experiments on gross anatomy, pathological tissue, and immunohistochemistry, electronic speculum etc. The ophthalmologists and researchers can also benefit from the clinical cases. We hope this book serves as a clinical guidance with practical significant for the understanding, prevention and diagnosis of glaucoma.
Current Developments in Glaucoma Surgery and MIGS
Successful interventional glaucoma remains a sought-after goal for the glaucoma clinician for many reasons. Medical costs, compliance, and adherence remain major barriers for the treatment of our patients. A truly definitive treatment for glaucoma is most likely to be largely surgical, as it is doubtful that patients will continue to use glaucoma drugs in the future for anything other than transient lowering of intraocular pressure. In the coming era, it seems probable that neuroprotection and neurorestoration will be combined with MIGS to lower pressure. The different types of MIGS are increasing in proportion to their efficacy. To date, there are no fewer than 12 choices available to glaucoma specialists. Choice of procedure depends on the underlying anatomy as well as the patient’s individual characteristics. Truthfully, the number of available surgeries depends upon their taxonomy. Most are based on the outflow system and the canal, as illustrated in this book.
Advances in Ophthalmology and Optometry, E-Book 2022
In this issue, guest editors bring their considerable expertise to this important topic. Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.
Advances in Ophthalmology and Optometry, E-Book 2021
Advances in Ophthalmology and Optometry reviews the most current practices in both ophthalmology and optometry. A distinguished editorial board, headed by Dr. Myron Yanoff, identifies key areas of major progress and controversy and invites expert ophthalmologists and optometrists to contribute original articles devoted to these topics. Broken into sections, this sixth volume in the series covers topics within each of the following categories: Optometry, Cataracts, Pediatrics, Ophthalmic Pathology & Ocular Oncology, Vitreoretinal Disease, Glaucoma, Neuro-ophthalmology, Oculoplastics, and Uveitis.
Ocular Blood Flow in Glaucoma
This is the sixth World Glaucoma Association Consensus. The relationship between ocular blood flow and glaucoma has been discussed for more than a century, and still it uniformly fuels debates at glaucoma meetings throughout the world. Clearly, the results of this report will have broad and significant impact on glaucoma research and clinical practice. The global faculty, consisting of leading authorities on the scientific and clinical aspects of ocular blood flow, have met in Fort Lauderdale on May 2, 2009 to discuss the reports and refine the consensus statements.
Anterior Segment Optical Coherence Tomography
High-speed anterior segment optical coherence tomography (OCT) offers a non-contact method for high resolution cross-sectional and three-dimensional imaging of the cornea and the anterior segment of the eye. As the first text completely devoted to this topic, Anterior Segment Optical Coherence Tomography comprehensively explains both the scientific principles and the clinical applications of this exciting and advancing technology. Anterior Segment Optical Coherence Tomography enhances surgical planning and postoperative care for a variety of anterior segment applications by expertly explaining how abnormalities in the anterior chamber angle, cornea, iris, and lens can be identified and evalu...
The Glaucoma Book
Complete evidence-based medical and surgical management of glaucoma for both the general ophthalmologist in practice and residents The only book that covers the new generation of glaucoma procedures including trabectome, trabecular bypass and canaloplasty, by the experts who developed them Includes the latest laser treatments for glaucoma including micro diode and titanium saphire trabeculoplasty as well as laser from an external approach The most comprehensive coverage of the optic nerve and the importance of nerve fiber layer hemorrhage Provides an integrated approach to neovascular glaucoma merging treatment to the retina, with the use of new anti-VEGF drugs, tubes, and shunts to achieve the best outcome Integrates clinical science with basic science to outline the next steps in glaucoma therapy
Ocular Fluid Dynamics
The chapters in this contributed volume showcase current theoretical approaches in the modeling of ocular fluid dynamics in health and disease. By including chapters written by experts from a variety of fields, this volume will help foster a genuinely collaborative spirit between clinical and research scientists. It vividly illustrates the advantages of clinical and experimental methods, data-driven modeling, and physically-based modeling, while also detailing the limitations of each approach. Blood, aqueous humor, vitreous humor, tear film, and cerebrospinal fluid each have a section dedicated to their anatomy and physiology, pathological conditions, imaging techniques, and mathematical mod...
